Evidence map›Paper›PMID 40265944›Full record

ArticleApplied and environmental microbiology2025

Dual roles of glycine betaine, dimethylglycine, and sarcosine as osmoprotectants and nutrient sources for

Heather E Thomas, Katherine E Boas Lichty, Gary P Richards, E Fidelma Boyd

Abstract read
In one paragraph

Article in Applied and environmental microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Metabolic response ofFrontiers in microbiology · 2026
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors.

Heather E ThomasDepartment of Biological Sciences, University of Delaware, Newark, Delaware, USA.
Katherine E Boas LichtyDepartment of Biological Sciences, University of Delaware, Newark, Delaware, USA.
Gary P RichardsU.S. Department of Agriculture, Agricultural Research Service, Dover, Delaware, USA.ORCID 0000-0003-1068-0874
E Fidelma BoydDepartment of Biological Sciences, University of Delaware, Newark, Delaware, USA.ORCID 0000-0001-7435-4897

Funding

CHEMISTRY-BIOLOGY INTERFACE PREDOCTORAL TRAININGT32GM008550 · NIGMS · UNIVERSITY OF DELAWARE · PI BAHNSON, BRIAN J · 1994 to 2018
$5.0M
Chemistry-Biology Interface Predoctoral Training Grant 2024-2029T32GM133395 · NIGMS · UNIVERSITY OF DELAWARE · PI Catherine Leimkuhler Grimes · 2019 to 2026
$3.7M
NIGMS NIH HHS T32 GM008550NIGMS NIH HHS T32 GM133395
6 · The paper itself

Abstract

Bacteria respond to osmotic stress by intracellularly accumulating low molecular weight compounds called compatible solutes, also known as osmolytes. Glycine betaine (

Indexed as

BetaineGlycineSarcosineVibrioBacterial ProteinsNutrientsOsmotic PressureBacterial ProteinsBetainedimethylglycineGlycineNutrientsSarcosinecatabolism clusterscompatible solutesdimethyl glycinemarine bacterianutrientssarcosine

Identifiers

PMID40265944
PMCPMC12093977

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.