ArticleLasers in surgery and medicine2025
The 730 nm Picosecond Titanium Sapphire Laser for Treatment of Kratom-Induced Hyperpigmentation.
Article in Lasers in surgery and medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed.
- Novel Histopathologic Features of Diffuse Blue-Gray Hyperpigmentation Associated With Kratom Use: A Case Report and Literature Review.Journal of cutaneous pathology · 2026Review
- Photodistributed Hyperpigmentation in a Chronic Kratom User: Histologic and Elemental Characterization.Journal of cutaneous pathology · 2026Article
- Kratom Cutaneous Hyperpigmentation: An Emerging Dermatosis for Dermatopathologists and Dermatologists to Recognize.Journal of cutaneous pathology · 2026Article
- Management of kratom-induced dyspigmentation with the 1064-nm picosecond laser.JAAD case reports · 2026Article
- Kratom-Induced Hyperpigmentation: An Emerging Clinicopathologic Pattern.Journal of cutaneous pathology · 2026Article
- Chronic photodistributed hyperpigmented patches in a middle-aged man.JAAD case reports · 2025Article
Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
objectivesThis case series reports the use of the 730-nm picosecond titanium-sapphire laser in the treatment of kratom-induced hyperpigmentation, a dermatological side effect associated with the use of Mitragyna speciosa, which remains poorly understood.
methodsA series of patients with kratom-induced hyperpigmentation were treated using the 730-nm picosecond titanium-sapphire laser. Treatment outcomes were documented by assessing the degree of pigmentation improvement and noting the occurrence of any adverse effects or recurrence of hyperpigmentation.
resultsAll patients showed significant improvement in the appearance of hyperpigmentation following treatment. No adverse effects or recurrence of hyperpigmentation were observed during the follow-up period.
conclusionsThis case series represents the first documented use of the 730-nm picosecond titanium-sapphire laser for treating kratom-induced hyperpigmentation. The laser's precision and minimal tissue disruption suggest it as a promising treatment option for this challenging dermatological side effect.
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Registered trials
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