ArticleJournal of child and adolescent psychiatric nursing : official publication of the Association of Child and Adolescent Psychiatric Nurses, Inc2025
The Impact of Adversity and Family Conflict on Risk for Future Substance Use Among Young Adolescents in the Adolescent Brain Cognitive Development Study (ABCD Study): A Cohort Analysis.
Article in Journal of child and adolescent psychiatric nursing : official publication of the Association of Child and Adolescent Psychiatric Nurses, Inc, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
3 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Understanding adverse childhood experiences within the first decade of the ABCD study: A systematic review.Developmental cognitive neuroscience · 2026Pooled it
- The role of peer influence in shaping developmental trajectories of substance use expectancies in early adolescence.Psychology of addictive behaviors : journal of the Society of Psychologists in Addictive Behaviors · 2026Article
- Individual Contributions of Adverse Childhood Experiences to Adolescent Substance Use.Substance use & misuse · 2026Article
Corrections and comments
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Authors and funding
8 authors.
Funding
Abstract
problemEarly initiation of substance use (
methodsMixed-effects modeling was used to analyze self-report data collected from adolescents and parents at baseline and 3-year follow-up (Y3) in the Adolescent Brain Cognitive Development Study (ABCD Study) (Data Release 5.1, 2016-2022, US).
findingsAfter adjusting for socio-demographic covariates, significant positive associations were found between adolescent ACEs score at baseline (ages 9-10) and risk for future alcohol (b = 0.03, p < 0.001), cigarette/e-cigarette (b = 0.04, p < 0.001), and marijuana use (b = 0.06, p < 0.001) at Y3 (ages 12-13) (n = 10,213 dyads). Family conflict reported at baseline was not found to moderate these associations.
conclusionsCumulative ACEs exposure was associated with increased risk for future alcohol, cigarette/e-cigarette, and marijuana use among a national sample of young adolescents. Findings highlight the potential for trauma-informed, developmentally appropriate preventative interventions to mitigate risk for future substance use among adversity-impacted adolescents.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.