Evidence map›Paper›PMID 40265601›Full record

ArticleJournal of the American Heart Association2025

Spectrum of Coronary Artery Involvement With Multisystem Inflammatory Syndrome in Children Versus Kawasaki Disease.

Simon Lee, Ashraf S Harahsheh, Geetha Raghuveer, Michael A Portman, Arash A Sabati, Michael Khoury, Nagib Dahdah, Marianna Fabi, Supriya S Jain, Audrey Dionne and 12 more

Abstract readComparative Study
In one paragraph

Article in Journal of the American Heart Association, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
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  3. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors.

Simon LeeAnn & Robert H. Lurie Children's Hospital of Chicago IL USA.ORCID 0000-0002-8032-0981
Ashraf S HarahshehChildren's National Hospital The George Washington University School of Medicine & Health Sciences Washington DC USA.ORCID 0000-0002-2622-573X
Geetha RaghuveerChildren's Mercy Hospital Kansas City MO USA.
Michael A PortmanSeattle Children's Research Institute Seattle WA USA.ORCID 0000-0002-8168-3725
Arash A SabatiPhoenix Children's Phoenix AZ USA.ORCID 0000-0002-8146-6819
Michael KhouryDepartment of Pediatrics University of Alberta Edmonton AB Canada.ORCID 0000-0001-6112-6860
Nagib DahdahDivision of Pediatric Cardiology, CHU Sainte-Justine University of Montreal QC Canada.ORCID 0000-0001-7715-3169
Marianna FabiPediatric Emergency Unit IRCCS Azienda Ospedaliero-universitaria di Bologna Italy.ORCID 0000-0002-2727-3506
Supriya S JainNew York Medical College - Maria Fareri Children's Hospital at Westchester Medical Center New York Valhalla NY USA.ORCID 0000-0002-0582-4119
Audrey DionneDepartment of Cardiology, Boston Children's Hospital, Department of Pediatrics Harvard Medical School Boston MA USA.ORCID 0000-0003-2864-1830
Kyle RunecklesTed Rogers Computational Program, Peter Munk Cardiac Centre, Ted Rogers Centre for Heart Research, The Hospital for Sick Children University Health Network Toronto ON Canada.
Frederic DallaireUniversite de Sherbrooke and Centre de recherche du Centre hospitalier universitaire de Sherbrooke QC Canada.ORCID 0000-0002-0489-2523
Nadine F ChoueiterChildrens Hospital at Montefiore Bronx NY USA.
Tyler H HarrisUPMC Children's Hospital of Pittsburgh PA USA.ORCID 0000-0002-0046-3334
Matthew D EliasDivision of Cardiology Children's Hospital of Philadelphia PA USA.ORCID 0000-0002-9534-2809
Anji T YetmanChildren's Nebraska Omaha NE USA.ORCID 0000-0001-6853-578X
Balasubramanian SundaramKanchi Kamakoti Childs Trust Hospital Chennai India.ORCID 0000-0001-7607-942X
Luis M Garrido-GarciaInstituto Nacional de Pediatria Mexico City Mexico.ORCID 0000-0001-7325-8801
Nilanjana MisraCohen Children's Medical Center of NY, Northwell Health Queens NY USA.ORCID 0000-0002-7575-9180
Cedric ManlhiotBlalock-Taussig-Thomas Congenital Heart Center at Johns Hopkins University Baltimore MD USA.
Pedrom FaridLabatt Family Heart Centre, The Hospital for Sick Children, Department of Pediatrics University of Toronto ON Canada.ORCID 0000-0002-3927-5461
Brian W McCrindleLabatt Family Heart Centre, The Hospital for Sick Children, Department of Pediatrics University of Toronto ON Canada.ORCID 0000-0001-6485-6551

Funding

Einstein-Montefiore Clinical and Translational Science Award HubUM1TR004400 · NCATS · ALBERT EINSTEIN COLLEGE OF MEDICINE · PI Jessica Kahn, Mimi Y Kim · 2023 to 2026
$17.3M
NCATS NIH HHS UM1 TR004400
6 · The paper itself

Abstract

backgroundThere is significant overlap in clinical features between multisystem inflammatory syndrome in children (MIS-C) and Kawasaki disease (KD). We sought to compare the prevalence, severity, and associated factors for coronary artery (CA) involvement. METHODS AND

resultsFrom January 1, 2020 through January 31, 2023, 1191 patients with MIS-C and 554 patients contemporaneously diagnosed with KD were enrolled into the International Kawasaki Disease Registry. Demographic and clinical features, laboratory values, maximum

conclusionsCA involvement for patients with MIS-C was less prevalent and milder in severity compared with contemporaneous patients with KD, with fewer associated factors, and a high prevalence of regression to a normal luminal dimension.

Indexed as

Coronary AneurysmCoronary Artery DiseaseCoronary VesselsMucocutaneous Lymph Node SyndromeSystemic Inflammatory Response SyndromeChildChild, PreschoolCOVID-19FemaleHumansInfantMalePrevalenceRegistriesRetrospective StudiesRisk Factorscoronary aneurysmKawasaki diseaseKawasaki disease registry

Identifiers

PMID40265601
PMCPMC12184260

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.