Evidence map›Paper›PMID 40265571›Full record

ArticleeLife2025

SFSWAP is a negative regulator of OGT intron detention and global pre-mRNA splicing.

Ashwin Govindan, Nicholas K Conrad

Abstract read
In one paragraph

Article in eLife, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Ashwin GovindanDepartment of Microbiology, University of Texas Southwestern Medical Center, Dallas, United States.ORCID https://orcid.org/0000-0003-1759-707X
Nicholas K ConradDepartment of Microbiology, University of Texas Southwestern Medical Center, Dallas, United States.ORCID https://orcid.org/0000-0002-8562-0895

Funding

Mechanisms of KSHV posttranscriptional gene regulationR01AI123165 · NIAID · UT SOUTHWESTERN MEDICAL CENTER · PI CONRAD, NICHOLAS K · 2016 to 2025
$4.5M
Mechanisms regulating KSHV transcription elongation and terminationR01AI153175 · NIAID · UT SOUTHWESTERN MEDICAL CENTER · PI CONRAD, NICHOLAS K · 2021 to 2025
$2.3M
New tools for studying GlcNAc biologyU01CA242115 · NCI · UT SOUTHWESTERN MEDICAL CENTER · PI KOHLER, JENNIFER J · 2019 to 2021
$1.5M
Mechanisms of posttranscriptional regulation of SAM homeostasisR01GM127311 · NIGMS · UT SOUTHWESTERN MEDICAL CENTER · PI CONRAD, NICHOLAS K · 2019 to 2022
$1.4M
NCI NIH HHS U01 CA242115NIAID NIH HHS R01 AI123165NIAID NIH HHS R01 AI153175NIGMS NIH HHS R01 GM127311NIH HHS R01 AI123165NIH HHS R01 AI153175NIH HHS R01 GM127311NIH HHS U01 CA242115
6 · The paper itself

Abstract

O-GlcNAcylation is the reversible post-translational addition of β-

Indexed as

IntronsN-AcetylglucosaminyltransferasesRNA PrecursorsRNA SplicingRNA Splicing FactorsHumansN-AcetylglucosaminyltransferasesO-GlcNAc transferaseOGT protein, humanRNA PrecursorsRNA Splicing Factorschromosomesdecoy exongene expressionhumanintron retentionO-glcnacOGTSFSWAPsplicing

Identifiers

PMID40265571
PMCPMC12017769

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.