Evidence map›Paper›PMID 40265423›Full record

ReviewCurrent stem cell research & therapy2025

Simultaneous Co-transplantation for Highly Efficient Cell Therapy.

Ji-Hee Choi, Mingu Ryu, Sung-Hwan Moon

Abstract readReview
In one paragraph

Review in Current stem cell research & therapy, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Ji-Hee ChoiDepartment of Animal Science and Technology, Chung-Ang University, Anseong, Republic of Korea.
Mingu RyuDepartment of Animal Science and Technology, Chung-Ang University, Anseong, Republic of Korea.
Sung-Hwan MoonDepartment of Animal Science and Technology, Chung-Ang University, Anseong, Republic of Korea.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cell therapy involves transplantation of cells to replace damaged tissues and cells and is used in regenerative medicine. Since its introduction, numerous cell therapy modalities have been developed to treat various diseases, and cell therapy has shifted the paradigm of the treatment of degenerative and refractory diseases. However, it faces limitations in terms of long-term therapeutic effects and efficiency. To overcome these challenges, the concept of co-transplantation, which utilizes two different cell sources, has been proposed. Stem cell-based co-transplantation approaches have been extensively studied both experimentally and clinically for various diseases, including graftversus- host disease (GVHD), infertility, acute liver failure (ALF), and myocardial infarction (MI). These have yielded improved transplantation efficiency and stability compared to single-cell transplantation methods. This review examines the development and effectiveness of co-transplantation through its application in four diseases. Additionally, it discusses the clinical applicability of cotransplantation, explores future research directions, and highlights its potential benefits.

Indexed as

Cell- and Tissue-Based TherapyGraft vs Host DiseaseInfertilityLiver Failure, AcuteMyocardial InfarctionStem Cell TransplantationAnimalsHumansRegenerative MedicineCell therapyclinical applicationco-transplantationincurable disease.regenerative medicinetherapeutic efficacy

Identifiers

PMID40265423
PMCPMC12728527

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.