Evidence map›Paper›PMID 40265373›Full record

ArticleEuropean burn journal2025

Bioabsorbable Poly(vinyl alcohol)-Citric Acid Dressings: Wound Healing Studies in an Experimental In Vivo Model.

Jonalba Mendes Pereira, Emilia Angela Lo Schiavo Arisawa, Antônio Luiz Martins Maia Filho, José Figueredo-Silva, Nicoly Alves, Carolina Hahn da Silveira, Lucia Vieira

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in European burn journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jonalba Mendes PereiraInstituto de Pesquisa e Desenvolvimento, Universidade do Vale do Paraíba, Avenida Shishima Hifumi, 2911, Urbanova, São José dos Campos 12244-000, SP, Brazil.ORCID 0000-0002-6303-4254
Emilia Angela Lo Schiavo ArisawaInstituto de Pesquisa e Desenvolvimento, Universidade do Vale do Paraíba, Avenida Shishima Hifumi, 2911, Urbanova, São José dos Campos 12244-000, SP, Brazil.ORCID 0000-0003-3526-3890
Antônio Luiz Martins Maia FilhoBiotechnology and Biodiversity Research Center, State University of Piaui, R. Lucídio Freitas, 2791-Matinha, Teresina 64003-120, PI, Brazil.ORCID 0000-0001-6184-8003
José Figueredo-SilvaBiotechnology and Biodiversity Research Center, State University of Piaui, R. Lucídio Freitas, 2791-Matinha, Teresina 64003-120, PI, Brazil.ORCID 0000-0002-7117-8784
Nicoly AlvesInstituto de Pesquisa e Desenvolvimento, Universidade do Vale do Paraíba, Avenida Shishima Hifumi, 2911, Urbanova, São José dos Campos 12244-000, SP, Brazil.
Carolina Hahn da SilveiraInstituto de Pesquisa e Desenvolvimento, Universidade do Vale do Paraíba, Avenida Shishima Hifumi, 2911, Urbanova, São José dos Campos 12244-000, SP, Brazil.ORCID 0000-0002-4289-7368
Lucia VieiraInstituto de Pesquisa e Desenvolvimento, Universidade do Vale do Paraíba, Avenida Shishima Hifumi, 2911, Urbanova, São José dos Campos 12244-000, SP, Brazil.ORCID 0000-0002-9354-6533

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe wound healing process presents notable challenges for nursing teams, requiring extensive knowledge of wound care materials. A nanoparticle-free, bioabsorbable pol-yvinyl alcohol (PVA) with citric acid (CA) dressing produced by simple electrospin-ning was evaluated to treat acute wound healing in rats. This PVA-CA combination promotes crosslinking, increases the dressing capacity of absorption and confers heal-ing properties due to the citric acid antioxidant action.

methodsThe dressing was tested in a quantitative experiment on 1.9 cm acute dermatological lesions in rats (

resultsThe macroscopic and histological data on the third day showed similar characteristics in both groups; however, after fourteen days, the PVA-CA group exhibited complete healing, accompanied by recomposition of the skin layers, whereas the wounds in the CG did not close completely.

conclusionsThe results highlight that electrospun PVA-AC dressings improve healing outcomes and constitute a prom-ising and affordable solution, providing a suitable environment for tissue repair, re-ducing inflammatory cell infiltration, blood vessel formation, and restoration of epi-thelial tissue, reducing the time of the healing process of acute wounds.

Indexed as

bioabsorbabledressingspolyvinyl alcohol–citric acid (PVA-AC)wound healing

Identifiers

PMID40265373
PMCPMC12015917

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.