Evidence map›Paper›PMID 40265271›Full record

ArticleFuture medicinal chemistry2025

Synthesis and antimicrobial evaluation of hybrids methoxynaphthalene-

Andrew Matheus Frederico Rozada, Camila Maçon, Jonathan L A Santos, Raquel Manzotti Ferreira, Maria Luiza Fróes da Motta Dacome, Rinaldo Poncio Mendes, Flávio Augusto Vicente Seixas, Katiany Caleffi, Ernani Abicht Basso, Gisele de Freitas Gauze Bandoch

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In one paragraph

Article in Future medicinal chemistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Andrew Matheus Frederico RozadaInstitute of Exact and Earth Sciences, Federal University of Mato Grosso, Barra do Garças, MT, Brazil.ORCID 0000-0001-8151-7949
Camila MaçonSchool of Medicine, São Paulo State University - UNESP, Botucatu, SP, Brazil.
Jonathan L A SantosDepartment of Clinical Analysis & Biomedicine, State University of Maringa, Maringá, PR, Brazil.
Raquel Manzotti FerreiraChemistry Department, State University of Maringa, Maringá, PR, Brazil.
Maria Luiza Fróes da Motta DacomeDepartment of Clinical Analysis & Biomedicine, State University of Maringa, Maringá, PR, Brazil.
Rinaldo Poncio MendesSchool of Medicine, São Paulo State University - UNESP, Botucatu, SP, Brazil.
Flávio Augusto Vicente SeixasDepartment of Technology, State University of Maringá, Umuarama, PR, Brazil.
Katiany CaleffiDepartment of Clinical Analysis & Biomedicine, State University of Maringa, Maringá, PR, Brazil.
Ernani Abicht BassoChemistry Department, State University of Maringa, Maringá, PR, Brazil.
Gisele de Freitas Gauze BandochChemistry Department, State University of Maringa, Maringá, PR, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimsParacoccidioidomycosis is a neglected tropical disease caused by the fungi MATERIALS &

methodsStarting from the precursor block 2-methoxy-1-naphthaldehyde,

resultsThe antimicrobial activity was tested for nine

conclusionNew structures containing methoxynaphalene rings and phenol or substituted phenol or pyridine groups can be added to the chemolibrary of candidates for prototypes of drugs with antimicrobial activity against

Indexed as

Anti-Bacterial AgentsAntifungal AgentsHydrazonesNaphthalenesOxadiazolesMicrobial Sensitivity TestsMolecular StructureMycobacterium tuberculosisStructure-Activity Relationship1,3,4-oxadiazoleAnti-Bacterial AgentsAntifungal AgentsHydrazonesNaphthalenesOxadiazoles1,3,4-oxadiazoles compounds2-methoxynaphthalene ringantifungal activityantimycobacterium activityN-acylhydrazones compoundsParacoccidioidomycosis

Identifiers

PMID40265271
PMCPMC12506727

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.