Evidence map›Paper›PMID 40264786›Full record

SynthesisFrontiers in immunology2025

Preoperative glasgow prognostic score was an effective prognostic indicator in patients with biliary tract cancer.

Rongqiang Liu, Ling Wang, Jing Ye, Xinyi Li, Wangbin Ma, Ximing Xu, Jia Yu, Weixing Wang

Abstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Frontiers in immunology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Rongqiang Liu *Department of Hepatobiliary Surgery, Renmin Hospital of Wuhan University, Wuhan, Hubei, China.
Ling Wang *Cancer Center, Renmin Hospital of Wuhan University, Wuhan, Hubei, China.
Jing Ye *Department of Hepatobiliary Surgery, Renmin Hospital of Wuhan University, Wuhan, Hubei, China.
Xinyi LiDepartment of Hepatobiliary Surgery, Renmin Hospital of Wuhan University, Wuhan, Hubei, China.
Wangbin MaDepartment of Hepatobiliary Surgery, Renmin Hospital of Wuhan University, Wuhan, Hubei, China.
Ximing XuCancer Center, Renmin Hospital of Wuhan University, Wuhan, Hubei, China.
Jia YuDepartment of Hepatobiliary Surgery, Renmin Hospital of Wuhan University, Wuhan, Hubei, China.
Weixing WangDepartment of Hepatobiliary Surgery, Renmin Hospital of Wuhan University, Wuhan, Hubei, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The Glasgow Prognostic Score (GPS) is a well-established prognostic indicator that effectively reflects the inflammatory, nutritional, and immune status of cancer patients. GPS has been shown to be associated with survival outcomes in many different cancers. However, its prognostic significance in biliary tract cancer (BTC) remains unclear. This meta-analysis aims to explore the prognostic value of GPS in BTC patients. Methods: A systematic search was conducted in PubMed, Embase, and Web of Science to identify relevant studies. Survival data including overall survival (OS), disease-free survival (DFS) and recurrence-free survival (RFS) were the main observation indicators. Hazard ratios (HRs) with 95% confidence intervals (CIs) were extracted and pooled for meta-analysis. Results: A total of 16 articles incorporating 1919 patients were included in the study. High GPS was associated with poor OS (HR:2.00, 95% CI:1.62-2.48) and DFS/RFS (HR:2.50, 95% CI:1.71-3.65). Subgroup analysis further confirmed the prognosis value of GPS in BTC patients. Conclusions: GPS could serves as a valuable prognostic marker in BTC patients and may aid in risk stratification and treatment decision-making.

Indexed as

Biliary Tract NeoplasmsBiomarkers, TumorDisease-Free SurvivalHumansPreoperative PeriodPrognosisBiomarkers, Tumorbiliary tract cancerglasgow prognostic scoremeta-analysisprognosissurvival

Identifiers

PMID40264786
PMCPMC12011749

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.