Evidence map›Paper›PMID 40264669›Full record

ArticleFrontiers in pharmacology2025

Assessment of competencies of clinical research professionals and proposals to improve clinical research in Portugal.

Mónica Bogas, Joana Antas, Cátia Magalhães, Mafalda Revige, Liliana Guerra, Cheila Ribeiro, Rita Cunha Eça, Filipa Nunes, Ana Lopes, Luís Costa and 24 more

Abstract read
In one paragraph

Article in Frontiers in pharmacology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

34 authors.

Mónica BogasRoche Portugal, Amadora, Portugal.
Joana AntasRoche Portugal, Amadora, Portugal.
Cátia MagalhãesRoche Portugal, Amadora, Portugal.
Mafalda RevigeRoche Portugal, Amadora, Portugal.
Liliana GuerraAICIB - Agency for Clinical Research and Biomedical Innovation, Porto, Portugal.
Cheila RibeiroAICIB - Agency for Clinical Research and Biomedical Innovation, Porto, Portugal.
Rita Cunha EçaLearning Health, Hospital da Luz Lisboa, Lisboa, Portugal.
Filipa NunesLearning Health, Hospital da Luz Lisboa, Lisboa, Portugal.
Ana LopesCentro de Investigação Clínica, ULS Santa Maria, Lisboa, Portugal.
Luís CostaCentro de Investigação Clínica, ULS Santa Maria, Lisboa, Portugal.
Mónica Gonçalves2CA-Braga - Centro Clínico Académico de Braga, Braga, Portugal.
Jorge Pedrosa2CA-Braga - Centro Clínico Académico de Braga, Braga, Portugal.
Andreia CapelaUnidade de Investigação e Ensaios Clínicos, ULS Gaia e Espinho EPE, Vila Nova de Gaia, Portugal.
Tiago GregórioUnidade de Investigação e Ensaios Clínicos, ULS Gaia e Espinho EPE, Vila Nova de Gaia, Portugal.
Patrícia DiasUnidade de Inovação e Desenvolvimento, ULS Coimbra EPE, Coimbra, Portugal.
Tiago AlfaroUnidade de Inovação e Desenvolvimento, ULS Coimbra EPE, Coimbra, Portugal.
Ana PaisInstituto Português de Oncologia de Coimbra Francisco Gentil, Coimbra, Portugal.
Rui SoaresInstituto Português de Oncologia de Coimbra Francisco Gentil, Coimbra, Portugal.
Ana QueirósUnidade de Ensaios Clínicos do Centro Académico Clínico, ICBAS/ULS Santo António, Porto, Portugal.
Tiago TorresUnidade de Ensaios Clínicos do Centro Académico Clínico, ICBAS/ULS Santo António, Porto, Portugal.
Joana AssisCentro de Investigação do Instituto Português de Oncologia do Porto (CI-IPOP), Porto, Portugal.
Joana MaiaCentro de Investigação do Instituto Português de Oncologia do Porto (CI-IPOP), Porto, Portugal.
Margarida FerreiraCentro de Investigação, ULS São José EPE, Lisboa, Portugal.
Luís HortaCentro de Investigação, ULS São José EPE, Lisboa, Portugal.
Rita CarreiroRoche Portugal, Amadora, Portugal.
João AlmeidaRoche Portugal, Amadora, Portugal.
Maria João MeirelesRoche Portugal, Amadora, Portugal.
Carla LouçãoRoche Portugal, Amadora, Portugal.
Sofia AntónioRoche Portugal, Amadora, Portugal.
Catarina LopesRoche Portugal, Amadora, Portugal.
Pedro CoelhoRoche Portugal, Amadora, Portugal.
Rita CostaRoche Portugal, Amadora, Portugal.
Margarida SantanaRoche Portugal, Amadora, Portugal.
Nuno SousaAICIB - Agency for Clinical Research and Biomedical Innovation, Porto, Portugal.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Clinical studies are coordinated by multidisciplinary teams, which often lack adequate training and competencies. In this study, ROCHE and AICIB (Agency for Clinical Research and Biomedical Innovation) conducted a self-assessment survey aiming to evaluate the competency of clinical research professionals to conduct clinical research in Portugal and promote the identification of key actions to address priority gaps. Methods: Clinical research professionals from 10 Portuguese centres answered an electronic survey, adapted and translated from the Joint Task Force for Clinical Trial Competency (JTFCTC) framework. Representatives of the centres, ROCHE and AICIB held a meeting to discuss the survey results, identify priority gaps and propose recommendations. Results: A total of 109 participants answered the questionnaire with the following national geographical distribution: North ( Conclusion: This study was the first to assess clinical trial competency in Portugal, registering a high participation rate. The study highlights the need to develop a national plan of action, in a collaborative effort, between clinical research centres, universities, industry, regulatory authorities, national agencies, and patient organizations. This will not only contribute to elevate the quality of studies but also improve compliance with international standards, ultimately benefiting both researchers and patients.

Indexed as

clinical researchclinical trialscore competencyprofessional developmentself-assessmentthe Joint Task Force for Clinical Trial Competency

Identifiers

PMID40264669
PMCPMC12012263

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.