ArticleFrontiers in neurology2025
Five functional domains associated with gait performance in Parkinson's disease and lateral trunk flexion.
Article in Frontiers in neurology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: Lateral trunk flexion (LTF) is a common symptom of Parkinson's disease (PD). The sensory re-weighting system and sensory-motor function are poor in patients with PD and LTF, and this may cause gait impairment. However, the specific characteristics of gait impairment in patients with PD and LTF remain unclear. The aim of this study was to compare the characteristics of the gait functional domains between participants with PD with and without LTF. Methods: Fifty-eight patients with PD and Hoehn-Yahr grade 2-3 LTF were divided into two groups: the LTF group ( Results: The LTF angle, SVV angle; MDS-UPDRS-Part III total, rigidity, and axial scores; and the coefficients of variance for step length, step time, and stance time were significantly higher in the LTF group than in the No LTF group. No other significant differences were observed between the groups. Conclusion: Participants with PD and Hoehn-Yahr severity 2-3 LTF had greater gait variability than those without LTF, but maintained similar pace, rhythm, asymmetry, and postural control domains. Patients with PD and LTF may develop abnormal neural networks causing greater gait variability.
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