Evidence map›Paper›PMID 40264644›Full record

ReviewBioMed research international2025

Molecular Mechanisms of Intervertebral Disc Degeneration Induced by

Weichao Yang, Yude Xu, Yong Tan, Jinzhi Lin, Huan Chen, Shaojin Li, Haixiong Miao, Dongping Ye

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in BioMed research international, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Review
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Weichao YangGuangzhou Red Cross Hospital, Guangzhou Red Cross Hospital of Jinan University, Guangzhou, China.ORCID https://orcid.org/0009-0009-1617-0681
Yude XuDepartment of Pain Medicine, Guangzhou Red Cross Hospital, Guangzhou Red Cross Hospital of Jinan University, Guangzhou, China.
Yong TanGuangzhou Red Cross Hospital, Guangzhou Red Cross Hospital of Jinan University, Guangzhou, China.
Jinzhi LinGuangzhou Red Cross Hospital, Guangzhou Red Cross Hospital of Jinan University, Guangzhou, China.
Huan ChenGuangzhou Red Cross Hospital, Guangzhou Red Cross Hospital of Jinan University, Guangzhou, China.
Shaojin LiGuangzhou Red Cross Hospital, Guangzhou Red Cross Hospital of Jinan University, Guangzhou, China.
Haixiong MiaoGuangzhou Red Cross Hospital, Guangzhou Red Cross Hospital of Jinan University, Guangzhou, China.ORCID https://orcid.org/0009-0006-3491-6780
Dongping YeGuangzhou Red Cross Hospital, Guangzhou Red Cross Hospital of Jinan University, Guangzhou, China.ORCID https://orcid.org/0000-0002-2677-6267

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Intervertebral disc degeneration (IVDD), a prevalent degenerative disorder with substantial socioeconomic impacts, is closely linked to endplate inflammation and chronic low back pain. Its pathogenesis involves multifactorial mechanisms, including long-term chronic mechanical loading, external trauma, and hereditary factors. Emerging evidence highlights

Indexed as

Gram-Positive Bacterial InfectionsIntervertebral Disc DegenerationPropionibacterium acnesAnimalsApoptosisHumansInflammationInterleukin-1betaNLR Family, Pyrin Domain-Containing 3 ProteinInterleukin-1betaNLR Family, Pyrin Domain-Containing 3 Proteininflammationintervertebral disc degenerationmolecular mechanismPropionibacterium acnespyroptosis

Identifiers

PMID40264644
PMCPMC12014266

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.