Evidence map›Paper›PMID 40264511›Full record

ArticleFrontiers in cardiovascular medicine2025

The associations between skin advanced glycation end-products and Framingham cardiovascular risk in different age groups.

Yina Wang, Shangyan Liang, Ying Zhou, Xiumei Tang, Na Ye, Weilan Huang, Xixiang Tang, Boxiong Jiang, Yunfeng Pan

Abstract read
In one paragraph

Article in Frontiers in cardiovascular medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Yina Wang *Department of VIP Medical Service Center, Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, China.
Shangyan Liang *Department of VIP Medical Service Center, Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, China.
Ying Zhou *Department of VIP Medical Service Center, Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, China.
Xiumei TangDepartment of Health Management Center, Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, China.
Na YeDepartment of Health Management Center, Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, China.
Weilan HuangDepartment of Health Management Center, Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, China.
Xixiang TangDepartment of VIP Medical Service Center, Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, China.
Boxiong JiangDepartment of VIP Medical Service Center, Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, China.
Yunfeng PanDepartment of Rheumatology and Immunology, Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: Advanced glycation end-products (AGEs) may contribute to the pathogenesis of atherosclerotic cardiovascular disease (ASCVD), potentially influencing its development and progression differently at various life stages. This study aimed to elucidate the associations between AGEs and the risk of ASCVD across different age groups. Methods: In this cross-sectional study, 1,240 subjects were enrolled and divided into three groups (Group Ⅰ, 20-39 years old, Results: An increasing trend in skin AGEs was observed from Group Ⅰ to Group Ⅲ. Skin AGEs were significantly associated with ASCVD risk in all subjects (OR 1.029, 95% CI 1.003-1.056, Conclusion: Our study substantiates that skin AGEs play an important role as an independent risk factor for ASCVD, highlighting their significance beyond traditional risk assessment models, particularly in middle-aged and older populations.

Indexed as

atherosclerotic cardiovascular diseasedifferent age groupsFramingham cardiovascular risk scoreskin advanced glycation end-productsskin autofluorescence

Identifiers

PMID40264511
PMCPMC12011794

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.