Evidence map›Paper›PMID 40264448›Full record

ArticleAJOG global reports2025

Pregnancy outcomes following surgical repair of female genital fistula in Uganda.

Abner P Korn, Justus K Barageine, Hadija Nalubwama, Jaffer Okiring, Florence Nalubega, Shane Ian Asiimwe, Alphonsus Matovu, Alison M El Ayadi

Abstract read
In one paragraph

Article in AJOG global reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Abner P KornDepartment of Obstetrics, Gynecology and Reproductive Sciences, University of California San Francisco, San Francisco, CA (Korn and El Ayadi).
Justus K BarageineDepartment of Obstetrics and Gynaecology, College of Health Sciences, Makerere University, Kampala, Uganda (Barageine and Nalubwama).
Hadija NalubwamaDepartment of Obstetrics and Gynaecology, College of Health Sciences, Makerere University, Kampala, Uganda (Barageine and Nalubwama).
Jaffer OkiringInfectious Disease Research Collaboration, Kampala, Uganda (Okiring).
Florence NalubegaKitovu Hospital, Masaka, Uganda (Nalubega).
Shane Ian AsiimweArua Regional Referral Hospital, Arua, Uganda (Asiimwe).
Alphonsus MatovuMubende Regional Referral Hospital, Mubende, Uganda (Matovu).
Alison M El AyadiDepartment of Obstetrics, Gynecology and Reproductive Sciences, University of California San Francisco, San Francisco, CA (Korn and El Ayadi).

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Women developing genital fistula and undergoing fistula repair in sub-Saharan Africa and South Asia are largely of reproductive age, and fistula prevalence is highest in countries with high fertility and where social values are placed on childbearing. Optimizing women's health following female genital fistula and surgical repair requires further understanding of the risks to subsequent pregnancies and how to mitigate them, to enable women to achieve their desired family size without additional morbidity. Objective: We sought to contribute to the postfistula repair evidence base through estimating rates of spontaneous abortion and stillbirth as well as the associated risk factors of these adverse outcomes in pregnancies following fistula repair. Methods: We captured data on sociodemographic characteristics, obstetric and fistula history, and pregnancy and childbirth care and experiences, and outcomes for the first postrepair pregnancy from 302 women who became pregnant within 10 years following genital fistula repair, recruited from six fistula repair facilities in Uganda. We described sociodemographic characteristics, spontaneous abortion (pregnancy loss <20 weeks gestational age), and stillbirth (intrauterine fetal death at ≥20 weeks gestational age) and determined factors associated with these outcomes using logistic regression. We compared outcomes to two external data sources: a meta-analysis and propensity-score matched Ugandan women of reproductive-age. Results: Overall, 14% (43/302) of the participants had spontaneous abortions and 5% (12/255) had stillbirths in postrepair pregnancies. The spontaneous abortion rate in our study was higher compared to a recent meta-analysis; however, the stillbirth rate was not. The stillbirth rate in our study was 2.5 percentage-points higher compared to the general population (95% CI 0.2-4.9, Conclusion: Our results demonstrate that in the study setting, greater attention to high-quality, comprehensive pregnancy care and birth planning are critical for improving outcomes among women who have undergone fistula repair, including facilitation of elective cesarean section which is recommended for postrepair births. Additional investments must be made to strengthen women's health access and knowledge that supports their postfistula repair reproductive goals.

Indexed as

female genital fistulamiscarriageobstetric fistulapostrepairreproductive outcomespontaneous abortionstillbirthUganda

Identifiers

PMID40264448
PMCPMC12013486

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.