Evidence map›Paper›PMID 40264316›Full record

ReviewCurrent drug research reviews2026

Repositioning Drugs: A Computational Approach.

Bhawna Sharma, Iti Chauhan, Rohit Pandey, Raj Kumar Tiwari, Gaurav Kumar, Gaurav Pratap Singh

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current drug research reviews, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Bhawna SharmaDepartment of Pharmaceutics, Dr. K.N. Modi Institute of Pharmaceutical Education and Research, Modinagar, Ghaziabad, UP, India.ORCID 0000-0002-3132-2964
Iti ChauhanDepartment of Pharmaceutics, I.T.S College of Pharmacy, Muradnagar, Ghaziabad, UP, India.ORCID 0000-0002-4440-9903
Rohit PandeyDepartment of Pharmaceutical Chemistry, Dr. K.N. Modi Institute of Pharmaceutical Education and Research, Modinagar, Ghaziabad, UP, India.
Raj Kumar TiwariDepartment of Pharmacology, Dr. K.N. Modi Institute of Pharmaceutical Education and Research, Modinagar, Ghaziabad, UP, India.
Gaurav KumarSRM Modinagar College of Pharmacy, SRMIST, Delhi-NCR campus, Modinagar, Ghaziabad, UP, India.
Gaurav Pratap SinghDepartment of Pharmaceutics, Dr. K.N. Modi Institute of Pharmaceutical Education and Research, Modinagar, Ghaziabad, UP, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Computational drug repositioning has emerged as an efficient approach to discovering new indications for existing drugs, offering lower risk and cost compared to traditional drug discovery methods. Various computational approaches have been developed, including targetbased, gene-expression-based, phenome-based, and multi-omics-based methods. Recent advancements leverage diverse data sources, such as biomedical databases and online healthrelated information. Techniques incorporating drug structure and target information have shown promising results in predicting new drug indications. Despite significant progress, challenges remain, including data noise reduction, method ensemble, negative sample selection, and data sparseness. Overall, computational drug repositioning continues to be a valuable tool in drug discovery and development.

Indexed as

Computational BiologyDrug RepositioningDrug DiscoveryHumansbiomedical databasescomputational approachesdata sourcesdrug discovery and developmentDrug repositioningnoise reduction

Identifiers

PMID40264316

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.