Evidence map›Paper›PMID 40264107›Full record

ArticleBMC musculoskeletal disorders2025

Effects of new assembled titanium mesh cage on the improvement in biomechanical performance of single-level anterior cervical corpectomy and fusion: a finite element analysis.

Ke-Rui Zhang, Yi Yang, Ya-Qin Li, Li-Tai Ma, Bei-Yu Wang, Chen Ding, Yang Meng, Xin Rong, Ying Hong, Hao Liu

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC musculoskeletal disorders, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Trial
  2. Is preoperative cervical range of motion associated with cage subsidence after anterior cervical discectomy and fusion?European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Ke-Rui Zhang *Department of Orthopedic West China Hospital, Sichuan University, No. 37 Guo Xue Xiang, Chengdu , Sichuan, 610041, China.
Yi Yang *Department of Orthopedic West China Hospital, Sichuan University, No. 37 Guo Xue Xiang, Chengdu , Sichuan, 610041, China.
Ya-Qin LiSchool of Nursing, the Hongkong Polytechnic University, Hong Kong, China.
Li-Tai MaDepartment of Orthopedic West China Hospital, Sichuan University, No. 37 Guo Xue Xiang, Chengdu , Sichuan, 610041, China.
Bei-Yu WangDepartment of Orthopedic West China Hospital, Sichuan University, No. 37 Guo Xue Xiang, Chengdu , Sichuan, 610041, China.
Chen DingDepartment of Orthopedic West China Hospital, Sichuan University, No. 37 Guo Xue Xiang, Chengdu , Sichuan, 610041, China.
Yang MengDepartment of Orthopedic West China Hospital, Sichuan University, No. 37 Guo Xue Xiang, Chengdu , Sichuan, 610041, China.
Xin RongDepartment of Orthopedic West China Hospital, Sichuan University, No. 37 Guo Xue Xiang, Chengdu , Sichuan, 610041, China.
Ying HongDepartment of Operation Room, West China Hospital, Sichuan University, No. 37 Guo Xue Xiang, Chengdu , Sichuan, 610041, China.
Hao LiuDepartment of Orthopedic West China Hospital, Sichuan University, No. 37 Guo Xue Xiang, Chengdu , Sichuan, 610041, China. liuhao6304@126.com.

Funding

National Natural Science Foundation of China 82172522Postdoctoral Science Foundation of China 2020M673240Sichuan Province Science and Technology Support Program of China 2020YFS0089Sichuan Province Science and Technology Support Program of China NO.2020YFS0077
6 · The paper itself

Abstract

backgroundAnterior cervical corpectomy and fusion (ACCF) with Traditional Titanium Mesh Cages (TTMCs) can lead to complications such as cage subsidence, dysphagia, and implant-related issues. These complications suggest that the biomechanical stability of ACCF with TTMC may be insufficient. This study aims to evaluate whether a New Assembled Titanium Mesh Cage (NTMC) can improve the biomechanical performance after ACCF.

methodsACCF procedures using both TTMC and NTMC models were constructed and compared. The range of motion (ROM) of the surgical segments and stress peaks in various regions including the endplate, bone-screw interface, facet joints, and adjacent intervertebral discs were analyzed.

resultsThe use of NTMC significantly reduced the postoperative ROM of the surgical segments by 80.7%-82.0% compared to ACCF with TTMC. Additionally, stress peaks at the endplate, bone-screw interface, and facet contact force (FCF) were higher in ACCF with TTMC compared to NTMC. TTMC also induced higher stress peaks in the C3/4 and C6/7 intervertebral discs (ranging from 0.2009-6.961 MPa and 0.2477-4.735 MPa, respectively), followed by the NTMC (ranging from 0.1322-3.820 MPa and 0.2227-4.104 MPa, respectively).

conclusionsThe utilization of NTMC, which includes enlarged spacers and emulates endplate geometries, effectively reduces the risks of cage subsidence and instrument-related complications in ACCF. Furthermore, ACCF with NTMC also decreases the risks of dysphagia, facet joint degeneration, and adjacent disc degeneration during the follow-up period by altering the fixing method while maintaining construct stability.

Indexed as

Cervical VertebraeFinite Element AnalysisSpinal FusionSurgical MeshTitaniumBiomechanical PhenomenaHumansRange of Motion, ArticularTitaniumACCFAssembled titanium mesh cageCage subsidenceFinite elementImplant-related complications

Identifiers

PMID40264107
PMCPMC12016357

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.