ArticleBMC pediatrics2025
A new mortality score in preterm infants: the vasoactive inotropic score.
Article in BMC pediatrics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
2 citing papers in PubMed.
- Cardiorespiratory coupling during high-frequency oscillatory ventilation with volume guarantee in extremely preterm infants.European journal of pediatrics · 2026Article
- Center-specific variation in outcomes for extremely premature, extremely low birth weight neonates.Frontiers in pediatrics · 2025Article
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesThe aim of this study is to evaluate the predictive value of the vasoactive inotropic score (VIS) for mortality in extremely low birth weight (ELBW) preterm infants and to compare this value with the well-known Clinical Risk Index for Babies-II (CRIB-II) score.
methodsThis study was designed as a retrospective study. A total of 280 preterm infants weighing under 1000 g who were admitted to the neonatal intensive care unit over a five-year period were included in the study. For each patient, a CRIB-II score and VIS were calculated, and their ability to predict mortality was compared. To predict and compare the accuracy of the scoring systems, Receiver Operating Characteristic (ROC) analysis was used, and the area under the curve (AUC) was calculated.
resultsIn infants who died within the first 28 days after birth, the CRIB-II score (p < 0.001) and VISmax (p < 0.001) were higher compared with those who survived. The AUCs for the CRIB-II score and VIS in predicting mortality were 0.86/0.81, with cut-offs of > 12/ > 5, sensitivities of 79/70, specificities of 82/87, positive predictive values (PPVs) of 81/85, and negative predictive values (NPVs) of 80/75. There were no statistically significant differences between the AUC values of the CRIB-II score and VIS variables (p = 0.160).
conclusionThe VIS can predict mortality in ELBW preterm infants as accurately as the CRIB-II score can.
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Registered trials
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