ArticleBMC cancer2025
Bronchial arterial chemoembolization/infusion combined with iodine-125 brachytherapy in advanced non-small cell lung cancer: a promising salvage therapy after standard treatment failure.
Article in BMC cancer, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
2 citing papers in PubMed.
- Improved early response assessment of chemoimmunotherapy efficacy byEuropean journal of nuclear medicine and molecular imaging · 2026Article
- Analysis of clinicopathological characteristics in postoperative molecular residual disease-positive stage I non-small cell lung cancer patients.Journal of thoracic disease · 2026Article
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
objectivesTo evaluate the efficacy, safety and optimal intervention timing of bronchial arterial chemoembolization/infusion combined with iodine-125 brachytherapy for advanced non-small cell lung cancer after standard treatment failure. MATERIALS AND
methodsFrom January 2019 to April 2024, the eligible patients with advanced non-small cell lung cancer after standard treatment failure received bronchial arterial chemoembolization/infusion combined with iodine-125 brachytherapy, were included in this retrospective study. Objective response rate, disease control rate, progression-free survival, overall survival and adverse events served as the main indicators of assessment. According to the intervention timing of intervention for this combination therapy, they were divided into the early intervention subgroup and the late intervention subgroup. Statistical analyses were performed using R software (version 3.5.3).
resultsA total of 45 patients with the median age 66 years (11 women) were enrolled in this study. The objective response rate of three months after the combination therapy was 71.11% and disease control rate was 95.56%. The median progression-free survival of this cohort was 12 months and the median overall survival was 20 months. The progression-free survival (15.5 vs. 9 months, P = 0.007) and overall survival (27.5 vs. 15 months, P < 0.001) in the early intervention subgroup was significantly better than that in the late intervention subgroup. No severe complications occurred.
conclusionFor advanced non-small cell lung cancer after standard treatment failure, the combination of bronchial arterial chemoembolization/infusion and iodine-125 brachytherapy is a promising salvage therapy with good efficacy and safety.
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