SynthesisBMC pediatrics2025
Analysis of the causes of redo pull-through for recurrent constipation and the risk factors affecting the prognosis of the Hirschsprung's disease: a single-center retrospective study and systematic review.
Synthesis in BMC pediatrics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed.
- Clinical characteristics, pathological comorbidities, BMI-for-age Z-score, and machine learning-based exploration of postoperative enterocolitis in iIntestinal neuronal dysplasia: a 20-year retrospective study.Pediatric surgery international · 2026Article
- Surgical Complications in Hirschsprung Disease and the Impact of Botulinum Toxin Injection on Hirschsprung-Associated Enterocolitis.Journal of clinical medicine · 2026Article
- Research progress on continuous nursing care for children after radical surgery for Hirschsprung's disease.Frontiers in public health · 2026Review
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Authors and funding
12 authors.
Funding
Abstract
backgroundHirschsprung's disease (HSCR) is a congenital gastrointestinal disorder. Pull-through (PT) surgery, the primary treatment, often leads to recurrent constipation. The causes of redo pull-through (redo-PT) for recurrent constipation remain unclear, with limited research on follow-up outcomes and prognostic factors.
methodsWe searched "PubMed" and "Web of Science" for references using the title/abstract terms "Hirschsprung" and "Redo pull-through". We enrolled patients from the literature review group and our retrospective group who underwent redo-PT for recurrent constipation. A comparative analysis was conducted between two groups based on the clinical information for redo-PT.
resultsA total of 360 cases were collected from the references (327 patients) and our center (33 patients). Recurrent aganglionosis (RA) and Mechanical Obstruction (MO) were the primary reasons for redo-PT, accounting for 52.50% and 36.67%, respectively. When comparing the causes of redo-PT between the literature group and our center group, RA accounted for 49.85% and 75.76%, while MO accounted for 49.85% and 21.21%, respectively. Prognostic outcomes of 31 patients from our center were analyzed, revealing no significant associations between postoperative complications and gender, age, causes of redo pull-through, or surgical approach (P > 0.05).
conclusionsRecurrent constipation requiring redo-PT are predominantly caused by RA and MO. Gender, age, causes of redo pull-through, or surgical approach do not affect the prognosis of redo-PT. The laparoscopic approach demonstrated superior cosmetic outcomes compared to the laparotomy approach.
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