Evidence map›Paper›PMID 40264005›Full record

ArticleBMC geriatrics2025

Associated factors of oral frailty in older adults with long-term T2DM duration of more than 10 years.

Jian Yu, Anna Ye, Yang Fei, Dandan Wang, Yu Zhang, Xianwen Li

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In one paragraph

Article in BMC geriatrics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Jian Yu *Department of Endocrinology, The First Affiliated Hospital with Nanjing Medical University (Jiangsu Province Hospital), Nanjing, LA, 210029, China.
Anna Ye *Department of Endocrinology, The First Affiliated Hospital with Nanjing Medical University (Jiangsu Province Hospital), Nanjing, LA, 210029, China.
Yang FeiSchool of Nursing, Nanjing Medical University, Nanjing, LA, 211166, China.
Dandan WangKangda College of Nanjing Medical University, Lianyungang, LA, 222000, China.
Yu ZhangChangZhou Vocational Institute of Textile and Garment, ChangZhou, LA, 213164, China.
Xianwen LiSchool of Nursing, Nanjing Medical University, Nanjing, LA, 211166, China. xwli0201@njmu.edu.cn.

Funding

Connotation Construction Project of Nanjing Medical University for Priority Academic of Nursing Science 2022-12Jiangsu Commission of Health Scientifc Research Project Z2020028Ministry of Education of Humanities and Social Science Project 22YJCZH089Philosophy and Social Science Research Projects of Jiangsu Universities 2022SJYB0298
6 · The paper itself

Abstract

objectiveTo identify the factors that affect oral frailty in older adults with type 2 diabetes mellitus (T2DM) with long-term disease duration of more than 10 years.

methodsThis cross-sectional study was conducted at a National Metabolic Center in China from October 2023 to March 2024. Participants with T2DM (aged ≥ 60 years and a disease duration > 10 years) underwent comprehensive dental examinations to assess functional natural teeth (FNT) counts and oral restoration behaviors. Oral frailty and cognitive function were assessed using the Oral Frailty Index-8 (OFI-8) and the Clock Drawing Test (CDT), respectively. Demographic and clinical data were extracted from the hospital information system. Univariate analysis and hierarchical multiple linear regressions were performed to identify associated factors of oral frailty.

resultsAmong 211 participants (mean age 71.22 ± 6.35 years, mean diabetes duration 20.95 ± 7.34 years), the mean OFI-8 score was 5.08 ± 2.29, with 74.4% scoring ≥ 4 (indicating oral frailty). The final regression model was statistically significant (F = 19.101, P < 0.001). In the regression model, a lower number of FNTs was significantly associated with higher oral frailty scores (β = -0.263, P < 0.001), whereas different oral restoration behaviors vary in the effect on oral frailty, fasting blood glucose (FBG) (β = 0.131, P = 0.014) and cognitive impairment (β = 0.255, P < 0.001) were positively associated with OFI-8 scores.

conclusionsThe study found that older adults with T2DM and a disease duration exceeding 10 years had a higher likelihood of exhibiting oral frailty. Individuals with fewer FNTs and those exhibiting cognitive impairment are the potential intervention targets to be concerned. Strict glycemic control and timely oral restoration are recommended to reduce oral frailty incidence in this population. CLINICAL TRIAL NUMBER: Not applicable.

Indexed as

Diabetes Mellitus, Type 2FrailtyOral HealthAgedAged, 80 and overChinaCross-Sectional StudiesFemaleHumansMaleMiddle AgedTime FactorsCognitive impairmentOlder adultsOral frailtyType 2 diabetes mellitus (T2DM)

Identifiers

PMID40264005
PMCPMC12013054

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.