Evidence map›Paper›PMID 40264003›Full record

ArticleBMC cardiovascular disorders2025

Heart failure outcomes in Sub-Saharan Africa: a scoping review of recent studies conducted after the 2022 AHA/ACC/HFSA guideline release.

Djibrilla Siddikatou, Edgar Mandeng Ma Linwa, Valérie Ndobo, Clovis Nkoke, Sidick Mouliom, Marie Solange Ndom, Ali Abas, Félicité Kamdem

Abstract readScoping Review
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC cardiovascular disorders, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Review
  4. Article
  5. Article
  6. Article
  7. Observational
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Djibrilla SiddikatouFaculty of Health Sciences, University of Buea, Buea, Cameroon.
Edgar Mandeng Ma LinwaFaculty of Health Sciences, University of Buea, Buea, Cameroon. macadamcity_2007@yahoo.fr.
Valérie NdoboFaculty of Medicine and Biomedical Sciences, University of Yaoundé I, Yaoundé, Cameroon.
Clovis NkokeFaculty of Health Sciences, University of Buea, Buea, Cameroon.
Sidick MouliomFaculty of Medicine and Pharmaceutical Sciences, University of Douala, Douala, Cameroon.
Marie Solange NdomFaculty of Medicine and Pharmaceutical Sciences, University of Douala, Douala, Cameroon.
Ali AbasFaculty of Medicine and Biomedical Sciences, University of Garoua, Garoua, Cameroon.
Félicité KamdemFaculty of Medicine and Pharmaceutical Sciences, University of Douala, Douala, Cameroon.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundHeart failure (HF) in Sub-Saharan Africa (SSA) presents unique challenges, with high prevalence and distinct epidemiological features compared to high-income settings. Despite its burden, recent comprehensive data are lacking, especially amidst recent 2022 AHA/ACC/HFSA guideline release. This scoping review aims to map the literature on HF in SSA, focusing on aetiologies, structural abnormalities, management practices, and outcomes to identify research gaps and inform clinical practice.

methodsStudies from 2022-2024 published in English or French were included, covering adult patients > 18 years, all study designs except case reports. Studies not reporting any outcomes or focusing solely on one HF subtype were excluded. Literature from all SSA countries was searched using a FACET approach in databases including PubMed, Google Scholar, Cochrane and Scopus.

resultsTen studies, evaluating 2039 patients, were analysed. Dilated cardiomyopathy (DCM), and Hypertensive cardiomyopathy (HCM) emerged as prominent aetiologies. Rheumatic heart disease was reported in only four studies. Common issues included high rates of electrolyte disturbances and anemia, which influenced patient outcomes. Guideline adherence exhibited significant deficiencies, notably with a suboptimal prescription rate of SGLT2 inhibitors (8.3-24.7%). Mortality rates ranged from 3.7% to 19%, linked to factors like low blood pressure and electrolyte imbalances. Hospital stays were variable but significant rehospitalization were common within 8-15 days post discharge and associated with non-compliance and lifestyle factors.

conclusionHCM and DCM are prevalent heart failure aetiologies in SSA. Longitudinal studies are recommended to contextualise aetiological diagnosis and validate prognostic tools amidst limited resources. Enhanced guideline adherence, hypertension control and efficient post-discharge care are essential to reduce morbidity and mortality.

Indexed as

Heart FailurePractice Guidelines as TopicPractice Patterns, Physicians'Africa South of the SaharaFemaleGuideline AdherenceHumansMaleMiddle AgedPrevalenceRisk FactorsTime FactorsTreatment OutcomeAetiologiesGuideline adherenceHeart failureMortality ratesSub-Saharan Africa

Identifiers

PMID40264003
PMCPMC12012955

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.