Evidence map›Paper›PMID 40263921›Full record

ReviewChemical record (New York, N.Y.)2025

Woodward and Hoffmann. Hoffmann and Woodward. A Close Collaboration Had Yet to Begin.

Jeffrey I Seeman

Abstract readReview
In one paragraph

Review in Chemical record (New York, N.Y.), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Jeffrey I SeemanDepartment of Chemistry, University of Richmond, Richmond, Virginia, 23173, USA.ORCID https://orcid.org/0000-0003-0395-2536

Funding

Memorial Library at the University of Richmond
6 · The paper itself

Abstract

In 1965, R. B. Woodward and Roald Hoffmann published five communications in the Journal of the American Chemical Society in which they outlined the mechanisms of electrocyclizations, cycloadditions, and sigmatropic reactions - today known as the Woodward-Hoffmann rules. Over the next several years, the organic chemistry community rushed to test the validity of the W-H rules and expand the range of reactions covered by them. Meanwhile, Woodward and Hoffmann were besieged with invitations to lecture and write expositions on these concepts. In this publication, I present an analysis of Woodward and Hoffmann's next publications in 1966 and 1967 on the W-H rules. Two of these publications were based on lectures Woodward or Hoffmann presented in late 1965 and 1966. I also discuss their own continuing research on the topic in this time period (all by Hoffmann; none by Woodward). I conclude that the assumed intimate collaboration of Woodward and Hoffmann had actually not yet begun.

Indexed as

collaborationsHistory of chemistrypericyclic reactionsWoodward-Hoffmann rules

Identifiers

PMID40263921
PMCPMC12067179

What OpenQuestion holds

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LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.