Evidence map›Paper›PMID 40263763›Full record

ArticlePediatric blood & cancer2025

Baseline Characteristics of Parents Enrolled in Children's Oncology Group Study ACCL20N1CD: Financial Toxicity During Treatment for Pediatric Acute Lymphoblastic Leukemia in the United States.

Sheila Judge Santacroce, Melissa P Beauchemin, Olivia Ponce, Lingyun Ji, Subhash Ramakrishnan, Kira Bona, Yudy Muñeton-Castaño, Joanna M Robles, Sarah Vargas, Crystal De Los Santos and 4 more

Abstract read
In one paragraph

Article in Pediatric blood & cancer, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Factors associated with unplanned healthcare encounters in pediatric cancer patients.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
    Trial
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Sheila Judge SantacroceThe University of North Carolina at Chapel Hill School of Nursing, Chapel Hill, North Carolina, USA.
Melissa P BeaucheminColumbia University Mailman School of Nursing, New York, New York, USA.ORCID https://orcid.org/0000-0003-4058-1586
Olivia PonceChildren's Oncology Group (COG), Monrovia, California, USA.
Lingyun JiChildren's Oncology Group (COG), Monrovia, California, USA.
Subhash RamakrishnanChildren's Oncology Group (COG), Monrovia, California, USA.
Kira BonaDana-Farber Cancer Institute, Boston, Massachusetts, USA.ORCID https://orcid.org/0000-0001-5602-7059
Yudy Muñeton-CastañoDana-Farber Cancer Institute, Boston, Massachusetts, USA.
Joanna M RoblesWake Forest University School of Medicine, Winston-Salem, North Carolina, USA.
Sarah VargasChildren's Oncology Group (COG), Monrovia, California, USA.
Crystal De Los SantosDriscoll Children's Hospital, Corpus Christi, Texas, USA.
Beth FisherChildren's Healthcare of Atlanta, Atlanta, Georgia, USA.
Sarah AlexanderThe Hospital for Sick Children, Toronto, Ontario, Canada.ORCID https://orcid.org/0000-0002-9695-1702
Lillian SungThe Hospital for Sick Children, Toronto, Ontario, Canada.
Susan K ParsonsTufts University School of Medicine, Boston, Massachusetts, USA.

Funding

Towards a preventive cancer vaccine for children with constitutional mismatch repair deficiencyUG1CA189955 · NCI · PUBLIC HEALTH INSTITUTE · PI BRAD H POLLOCK, Michael E. Roth · 2014 to 2026
$62.5M
CTSA K12 Program at Wake ForestK12TR004931 · NCATS · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI Nicholette D. Allred · 2024 to 2026
$2.3M
Canada Research Chair in Pediatric Oncology Supportive CareChildren's Oncology Group NCORP Research Base 5UG1CA189955COG NCORP Research Base 3UG1CA189955-10S2NCATS NIH HHS K12 TR004931NCI NIH HHS UG1 CA189955
6 · The paper itself

Abstract

backgroundCosts to parents and associated financial distress may contribute to observed health disparities in pediatric oncology. We describe financial distress in a cohort of parents with children newly diagnosed with acute lymphoblastic leukemia (ALL) and identify factors contributing to high financial distress. PROCEDURES: Settings were 28 Children's Oncology Group practices in the National Cancer Institute Community Oncology Research Program. We included English- or Spanish-speaking parents of children with newly diagnosed ALL. Analyses focused on baseline surveys completed by parents during their child's ALL induction therapy. Survey items asked about socio-demographics, household material hardships, financial burden, financial distress, and financial coping behaviors.

resultsThe cohort included 104 parents. Most were female (87; 83.7%), White (68; 65.4%), non-Hispanic (50; 48.1%), and paid for their child's care with Medicaid or CHIP (60; 57.7%). Financial burden totaled greater than 15% of monthly gross household income for half (54, 51.5%), and 45 (43%) indicated high financial distress (score 1-4). Prevalent coping behaviors with health implications included cutting back on groceries (62, 59.6%) or other necessities (61, 58.7%). Parents who had poverty-level income (p = 0.0009), paid with Medicaid or CHIP (OR 3.0 [CI: 1.26, 7.13], p = 0.01), were unemployed (OR 2.5 [CI: 1.1, 5.7], p = 0.04), or lived where more than 50% of residents had socioeconomic disadvantages (OR 3.0 [CI: 1.13, 8.05], p = .03) were more likely to indicate high financial distress than others.

conclusionsDuring their child's ALL induction therapy, sizeable proportions of parents exhibited high financial burdens, high levels of financial distress, and multiple financial coping behaviors with health implications.

Indexed as

Cost of IllnessFinancial StressParentsPrecursor Cell Lymphoblastic Leukemia-LymphomaAdaptation, PsychologicalAdolescentAdultChildChild, PreschoolFemaleFollow-Up StudiesHumansInfantMalePrognosisUnited Statesfinancial burdenfinancial distresshealth disparitiessocial determinants of health

Identifiers

PMID40263763
PMCPMC12126849

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.