Evidence map›Paper›PMID 40263671›Full record

ArticleNursing open2025

Comparing Nurse-Led and Physician-Led Bilevel Positive Airway Pressure Management in Hypercapnic Respiratory Failure: A Retrospective Cohort Study.

Zhimin Zhao, Zhen Zhang, Xinlei Li, Bo Peng, Jinqian Xiong

Abstract read
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Article in Nursing open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Zhimin ZhaoSchool of Medicine, Henan Kaifeng College of Science Technology and Communication, Kaifeng, China.ORCID https://orcid.org/0009-0009-9347-7310
Zhen ZhangDepartment of Respiratory and Critical Medicine, The First Affiliated Hospital of Henan University, Kaifeng, China.ORCID https://orcid.org/0009-0007-4562-7332
Xinlei LiSchool of Medicine, Henan Kaifeng College of Science Technology and Communication, Kaifeng, China.
Bo PengDepartment of Respiratory and Critical Medicine, The First Affiliated Hospital of Henan University, Kaifeng, China.
Jinqian XiongDepartment of Respiratory and Critical Medicine, The First Affiliated Hospital of Henan University, Kaifeng, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimBilevel positive airway pressure (BiPAP) management is a cornerstone in treating acute hypercapnic respiratory failure, with varying outcomes depending on the care model. This retrospective cohort study aims to compare the effectiveness of nurse-led versus physician-led BiPAP management in this context.

designRetrospective cohort study.

methodsWe analysed medical records of 189 patients with acute hypercapnic respiratory failure treated with BiPAP between January 2020 and December 2022. Patients were divided into nurse-led (n = 101) and physician-led (n = 88) groups based on their BiPAP management leadership. Outcomes measured included arterial blood gas (ABG) parameter improvements, intubation rates, length of hospital stay and 30-day readmission rates. Statistical analysis involved chi-squared tests, t-tests, Mann-Whitney U tests and multivariable regression to adjust for confounders.

resultsBoth groups demonstrated significant improvements in ABG parameters, with no significant differences between groups. The nurse-led group exhibited a lower intubation rate (9.9% vs. 21.6%, p = 0.026) and higher patient satisfaction scores (median 8 vs. 6, p < 0.001). Mortality rates, complication rates and 30-day readmission rates were similar between the groups. Multivariable logistic regression confirmed the nurse-led group had a lower likelihood of intubation (AOR: 0.401, p = 0.032) and higher patient satisfaction (AOR: 7.770, p < 0.001). PATIENT OR PUBLIC CONTRIBUTION: Our findings indicate that nurse-led and physician-led BiPAP management strategies for acute hypercapnic respiratory failure are equally effective in terms of ABG improvement, intubation rates, hospital stay length, and readmission rates. This suggests that with adequate training and supervision, nurse-led BiPAP management can be as effective as physician-led management, offering a viable alternative in healthcare settings where physician resources are limited.

Indexed as

HypercapniaPhysiciansRespiratory InsufficiencyAgedCohort StudiesFemaleHumansMaleMiddle AgedRetrospective Studiesacute hypercapnic respiratory failureBiPAPclinical outcomesnon‐invasive ventilationnurse‐led carephysician‐led care

Identifiers

PMID40263671
PMCPMC12014393

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.