Evidence map›Paper›PMID 40263581›Full record

ArticleNature plants2025

Viral delivery of an RNA-guided genome editor for transgene-free germline editing in Arabidopsis.

Trevor Weiss, Maris Kamalu, Honglue Shi, Zheng Li, Jasmine Amerasekera, Zhenhui Zhong, Benjamin A Adler, Michelle M Song, Kamakshi Vohra, Gabriel Wirnowski and 8 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nature plants, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 59 papers.

0numbers the graph read from it
0cells of the map it votes in
59citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

59 citing papers in PubMed.

  1. Behind (cell) walls.Nature biotechnology · 2026
    Article
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  4. Review
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Virus-induced transgene- and tissue culture-free heritable genome editing in tomato.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  11. Article
  12. Article
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  14. Article
  15. Article
  16. Article
  17. Review
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  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Trevor WeissDepartment of Molecular, Cell and Developmental Biology, University of California at Los Angeles, Los Angeles, CA, USA.ORCID http://orcid.org/0000-0002-2373-0802
Maris KamaluDepartment of Molecular, Cell and Developmental Biology, University of California at Los Angeles, Los Angeles, CA, USA.ORCID http://orcid.org/0009-0009-8008-7196
Honglue ShiInnovative Genomics Institute, University of California, Berkeley, CA, USA.ORCID http://orcid.org/0000-0003-3847-1652
Zheng LiDepartment of Molecular, Cell and Developmental Biology, University of California at Los Angeles, Los Angeles, CA, USA.ORCID http://orcid.org/0000-0003-2174-7851
Jasmine AmerasekeraDepartment of Molecular, Cell and Developmental Biology, University of California at Los Angeles, Los Angeles, CA, USA.
Zhenhui ZhongDepartment of Molecular, Cell and Developmental Biology, University of California at Los Angeles, Los Angeles, CA, USA.ORCID http://orcid.org/0000-0002-8438-0375
Benjamin A AdlerInnovative Genomics Institute, University of California, Berkeley, CA, USA.
Michelle M SongDepartment of Molecular, Cell and Developmental Biology, University of California at Los Angeles, Los Angeles, CA, USA.ORCID http://orcid.org/0009-0003-4200-5774
Kamakshi VohraInnovative Genomics Institute, University of California, Berkeley, CA, USA.
Gabriel WirnowskiDepartment of Molecular, Cell and Developmental Biology, University of California at Los Angeles, Los Angeles, CA, USA.ORCID http://orcid.org/0009-0003-3860-1506
Sidharth ChitkaraDepartment of Molecular, Cell and Developmental Biology, University of California at Los Angeles, Los Angeles, CA, USA.ORCID http://orcid.org/0009-0001-0807-2186
Charlie AmbroseDepartment of Molecular, Cell and Developmental Biology, University of California at Los Angeles, Los Angeles, CA, USA.
Noah SteinmetzDepartment of Molecular, Cell and Developmental Biology, University of California at Los Angeles, Los Angeles, CA, USA.
Ananya SridharanDepartment of Molecular, Cell and Developmental Biology, University of California at Los Angeles, Los Angeles, CA, USA.
Diego SahagunDepartment of Molecular, Cell and Developmental Biology, University of California at Los Angeles, Los Angeles, CA, USA.
Jillian F BanfieldInnovative Genomics Institute, University of California, Berkeley, CA, USA.ORCID http://orcid.org/0000-0001-8203-8771
Jennifer A DoudnaInnovative Genomics Institute, University of California, Berkeley, CA, USA.ORCID http://orcid.org/0000-0001-9161-999X
Steven E JacobsenDepartment of Molecular, Cell and Developmental Biology, University of California at Los Angeles, Los Angeles, CA, USA. jacobsen@ucla.edu.ORCID http://orcid.org/0000-0001-9483-138X

Funding

National Science Foundation (NSF) 2334027
6 · The paper itself

Abstract

Genome editing is transforming plant biology by enabling precise DNA modifications. However, delivery of editing systems into plants remains challenging, often requiring slow, genotype-specific methods such as tissue culture or transformation

Indexed as

ArabidopsisGene EditingPlant VirusesRNA, Guide, CRISPR-Cas SystemsCRISPR-Cas SystemsGenome, PlantPlants, Genetically ModifiedTransgenesRNA, Guide, CRISPR-Cas Systems

Identifiers

PMID40263581
PMCPMC12095077

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.