Evidence map›Paper›PMID 40263460›Full record

ArticleNature reviews. Rheumatology2025

Targeting osteoarthritis where it hurts: the osteochondral junction.

Anne-Marie Malfait, Alia M Obeidat

Abstract read
In one paragraph

Article in Nature reviews. Rheumatology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Anne-Marie MalfaitDepartment of Internal Medicine, Division of Rheumatology, Rush University Medical Center, Chicago, IL, USA. anne-marie_malfait@rush.edu.
Alia M ObeidatDepartment of Internal Medicine, Division of Rheumatology, Rush University Medical Center, Chicago, IL, USA.ORCID http://orcid.org/0009-0007-9864-0119

Funding

Precision Mapping of Knee Pain in Osteoarthritis: Understanding differences between pain with activity and restUC2AR082186 · NIAMS · RUSH UNIVERSITY MEDICAL CENTER · PI LOTZ, MARTIN K, MALFAIT, ANNE-MARIE · 2022 to 2025
$11.9M
Osteoarthritis Progression And Sensory Pathway AlterationsR01AR064251 · NIAMS · RUSH UNIVERSITY MEDICAL CENTER · PI MALFAIT, ANNE-MARIE, MILLER, RICHARD J · 2013 to 2025
$7.6M
Molecular Pathways of Pain Generation in OsteoarthritisR01AR060364 · NIAMS · RUSH UNIVERSITY MEDICAL CENTER · PI MALFAIT, ANNE-MARIE · 2011 to 2025
$6.0M
Neurobiology Core CP30AR079206 · NIAMS · RUSH UNIVERSITY MEDICAL CENTER · PI Anne-Marie Malfait · 2021 to 2026
$4.7M
The role of Nerve-fibroblast communication in EDS painR21AR085242 · NIAMS · RUSH UNIVERSITY MEDICAL CENTER · PI MALFAIT, ANNE-MARIE · 2024 to 2024
$351k
NIAMS NIH HHS P30 AR079206NIAMS NIH HHS R01 AR060364NIAMS NIH HHS R01 AR064251NIAMS NIH HHS R21 AR085242NIAMS NIH HHS UC2 AR082186
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Identifiers

PMID40263460
PMCPMC12355372

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.