Evidence map›Paper›PMID 40263340›Full record

ArticleScientific reports2025

Executive functions and associated brain volumetry in children with persistent stunting and catch-up growth.

Beena Koshy, Vedha Viyas Thilagarajan, Roshan S Livingstone, Manikandan Srinivasan, Venkata Raghava Mohan, Rachel Beulah, Anitha Jasper, Sushil John, Gagandeep Kang

Abstract read
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Beena KoshyDevelopmental Paediatrics, Christian Medical College, Vellore, Tamil Nadu, 632004, India. beenakurien@cmcvellore.ac.in.
Vedha Viyas ThilagarajanDevelopmental Paediatrics, Christian Medical College, Vellore, Tamil Nadu, 632004, India.
Roshan S LivingstoneLow Cost Effective Care Unit, Christian Medical College, Vellore, Tamil Nadu, 632004, India.
Manikandan SrinivasanWellcome Trust Research Laboratory, Christian Medical College, Vellore, Tamil Nadu, 632004, India.
Venkata Raghava MohanDepartment of Community Health, Christian Medical College, Vellore, Tamil Nadu, 632004, India.
Rachel BeulahDevelopmental Paediatrics, Christian Medical College, Vellore, Tamil Nadu, 632004, India.
Anitha JasperDepartment of Radiodiagnosis, Christian Medical College, Vellore, Tamil Nadu, 632004, India.
Sushil JohnLow Cost Effective Care Unit, Christian Medical College, Vellore, Tamil Nadu, 632004, India.
Gagandeep KangDepartment of Community Health, Christian Medical College, Vellore, Tamil Nadu, 632004, India.

Funding

Bill and Melinda Gates Foundation OPP 47075Wellcome Trust DBT India Alliance IA/CPHI/19/1/504611
6 · The paper itself

Abstract

Early childhood stunting can result in sub-optimal executive functions (EF), affecting academic achievements and economic potential in later life. This study hypothesized that children always stunted (AS) at ages 2, 5 and 9 years had lower EF than those who were never stunted (NS). A birth-cohort in Vellore, India was followed up with periodic anthropometric and development/cognitive measures over 2, 5 and 9 years of age. Based on stunting status at these time points, children were classified as NS, stunted at 2 years and caught up by 5 years (S2N5), stunted at 2 and 5 years but caught up later (S5N9), and AS. At 9th year, children underwent neuroimaging using 3T MRI scanner and EF assessment using FAS phonemic fluency test, colour cancellation test and colour trials tests (CTT). From the original birth-cohort of 251, 205 children were reviewed at 9 years. FAS phonemic fluency test showed NS group had significantly higher test scores compared to AS (11.52 vs. 7.4, p = 0.02). In CTT, a significant difference in near misses score was observed between NS and AS groups (0.12 vs. 0.38, p = 0.03). Upon evaluating unimodal brain association areas, volumes of right occipital fusiform gyrus (9991 mm

Indexed as

BrainExecutive FunctionGrowth DisordersChildChild, PreschoolFemaleHumansIndiaMagnetic Resonance ImagingMaleNeuroimagingOrgan SizeBrain volumetryCatch-up growthChildhood stuntingExecutive functionsMagnetic resonance imaging

Identifiers

PMID40263340
PMCPMC12015276

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.