ArticleNature communications2025
Porous hierarchically ordered hydrogels demonstrating structurally dependent mechanical properties.
Article in Nature communications, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
15 citing papers in PubMed.
- Diblock/Triblock Composition Controls Pore Structure and Mechanical Response in Hierarchically Ordered Hydrogels.ACS applied polymer materials · 2026Article
- Multifunctional Intelligent Hydrogels Based on MnOGels (Basel, Switzerland) · 2026Article
- Ultrasoft, adhesive, pH-tunable hydrogel based on in situ functionalized laser-induced graphene for through-hair concurrent biosensing.Science advances · 2026Article
- High-performance hydrogels in orthopedics: Structural design, performance tuning, and clinical potential.Materials today. Bio · 2026Review
- Multifunctional polyoxomolybdate cluster loaded into hydrogel for augmented bone regeneration through synergistic immunomodulation and osteogenesis.Bioactive materials · 2026Article
- Porous material engineering through synthesis for smart sensor systems.Microsystems & nanoengineering · 2026Review
- Arresting Microphase Separation Encodes Material Mechanics by Sculpting Microarchitectures and Local Polymer Enrichment.Advanced materials (Deerfield Beach, Fla.) · 2026Article
- Ultrathin and ultrastrong hydrogel bioelectronic membranes.National science review · 2026Article
- 3D Printing of Cincau Perdu (Foods (Basel, Switzerland) · 2026Article
- Quantitative Assessment of Hydrogel Printability in Extrusion Bioprinting.Gels (Basel, Switzerland) · 2026Review
- Molecular clustering unlocks high-performance hydrovoltaics across temperatures from -35 °C to 80 °C.Nature communications · 2026Article
- Flexible Polymer Hydrogel Materials for Next-Generation Wearable Energy Storage Technologies.Gels (Basel, Switzerland) · 2025Review
- Bioprinted Recombinant Human-Collagen-Based In Vitro Skin Models for Assessing Effects of Nano-ZnO on Dermis.Gels (Basel, Switzerland) · 2025Article
- Applications of Conductive Polymer Hydrogels for Supercapacitor, Solar Cell, and Energy Conversion.Gels (Basel, Switzerland) · 2025Review
- Cellulose hydrogel with in-situ confined nanopores for boosting moist-electric conversion.Nature communications · 2025Article
Corrections and comments
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Authors and funding
8 authors.
Funding
Abstract
While hierarchical ordering is a distinctive feature of natural tissues and is directly responsible for their diverse and unique properties, efforts to synthesize biomaterials have primarily focused on using molecular-based approaches with little emphasis on multiscale structure. Here, we report a bottom-up self-assembly process to produce highly porous hydrogel fibers that resemble extracellular matrices both structurally and mechanically. Physically crosslinked nanostructured micelles form the walls of micrometer-sized water-rich pores with preferred orientation along the fiber direction. Low elastic moduli (<1 kPa), high elasticity (extending by more than 12 times the initial length), non-linear elasticity (e.g., hyperelasticity), and completely reversible extension are derived from unevenly distributed strain between the micrometer-sized pores and the polymer chains, which is reminiscent of cellular solids. Control of the material microstructure and orientation over many orders of magnitude (e.g., nm-μm), while holding the nanostructure constant, reveals how the multiscale structure directly impacts mechanical properties.
Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.