Evidence map›Paper›PMID 40263204›Full record

SynthesisSports medicine - open2025

Management of Anterior Cruciate Ligament Injuries in Children and Adolescents: A Systematic Review.

Hongfu Jin, Nouman Tahir, Shide Jiang, Herasimenka Mikhail, Volotovski Pavel, Masoud Rahmati, Seung Won Lee, Wenfeng Xiao, Yusheng Li

Abstract readSystematic Review
In one paragraph

Synthesis in Sports medicine - open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Pediatric ACL Injuries: A Current Concepts Review.Journal of clinical medicine · 2026
    Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Hongfu JinDepartment of Orthopedics, Xiangya Hospital of Central South University, Changsha, 410008, Hunan, China.
Nouman TahirDepartment of Orthopedics, Xiangya Hospital of Central South University, Changsha, 410008, Hunan, China.
Shide JiangDepartment of Orthopedics, Loudi Central Hospital, Loudi, Hunan, China.
Herasimenka MikhailRepublican Scientific and Practical Center of Traumatology and Orthopedics, Minsk, 220024, Belarus.
Volotovski PavelRepublican Scientific and Practical Center of Traumatology and Orthopedics, Minsk, 220024, Belarus.
Masoud RahmatiDepartment of Physical Education and Sport Sciences, Faculty of Literature and Huma n Sciences, Lorestan University, Khoramabad, Iran.
Seung Won LeeDepartment of Precision Medicine, Sungkyunkwan University College of Medicine, Suwon, Republic of Korea.
Wenfeng XiaoDepartment of Orthopedics, Xiangya Hospital of Central South University, Changsha, 410008, Hunan, China. xiaowenfeng@csu.edu.cn.
Yusheng LiDepartment of Orthopedics, Xiangya Hospital of Central South University, Changsha, 410008, Hunan, China. liyusheng@csu.edu.cn.

Funding

Fundamental Research Funds for the Central Universities of Central South University 2023ZZTS0229Hunan Young Talents of Science and Technology 2021RC3025National Clinical Research Center for Geriatric Disorders 2021KF02National Key R&D Program of China 2019YFA0111900National Natural Science Foundation of China 82072506, 92268115Project for Undergraduate Students of Hunan CX20230303
6 · The paper itself

Abstract

backgroundDue to rising sports participation, anterior cruciate ligament (ACL) tears are increasingly prevalent in children and adolescents. This systematic review aimed to evaluate and summarize the management strategies for ACL injuries in children and adolescents.

methodsA comprehensive search of PubMed, Embase, Web of Science, and Cochrane Library databases was conducted to identify studies reporting outcomes of ACL injuries in children and adolescents. Key outcomes were synthesized descriptively, including knee instability, secondary damage, growth disturbances, and return-to-sport (RTS) rates.

resultsA total of 7,507 publications were initially screened, with 105 studies involving 8294 children or adolescents satisfying the inclusion criteria. Conservative treatments were associated with elevated rates of knee instability (35.85-100%), secondary meniscal and cartilage damage, and long-term degenerative changes. Conversely, surgical interventions, including physeal-sparing and transphyseal techniques, demonstrated superior outcomes with lower instability rates (0-7.41%), fewer complications, and higher RTS rates (83.4-92.6%). Pooled RTS rates for conservative treatments were 44.0% (95%CI: 0.018-0.927), while physeal-sparing ACL reconstruction showed a pooled RTS rate of 92.6% (95%CI: 0.732-1.000) and transphyseal ACL reconstruction reported an RTS rate of 83.4% (95%CI: 0.722-0.924).

conclusionConservative management of ACL injuries in children and adolescents is linked to higher rates of knee instability, secondary meniscal and cartilage damage, and degenerative changes. In contrast, surgical interventions, such as physeal-sparing and transphyseal techniques, yield better outcomes in knee stability, complications reduction, and RTS rates. However, risks such as graft rupture, repeat surgeries, and potential growth disturbances emphasize the importance of tailoring surgical approaches to the patient's growth stage and anatomical characteristics.

Indexed as

ACLAnterior Cruciate LigamentPaediatricSkeletally ImmatureSurgery

Identifiers

PMID40263204
PMCPMC12014893

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.