Evidence map›Paper›PMID 40263197›Full record

ReviewInternational journal of clinical oncology2025

Safety of laparoscopic surgery for ovarian tissue cryopreservation in pediatric patients.

Haruhiro Kondo, Seido Takae, Shigeyuki Furuta, Miki Sakamoto, Juma Obayashi, Dai Keino, Kentaro Nakamura, Kunihide Tanaka, Takuya Kawaguchi, Mika Mori and 10 more

Abstract readReview
PubMed Publisher
In one paragraph

Review in International journal of clinical oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors.

Haruhiro Kondo *Department of Obstetrics and Gynecology, St. Marianna University School of Medicine, 2-16-1 Sugao, Miyamae-Ku, Kawasaki, Kanagawa, 216-8511, Japan.
Seido Takae *Department of Obstetrics and Gynecology, St. Marianna University School of Medicine, 2-16-1 Sugao, Miyamae-Ku, Kawasaki, Kanagawa, 216-8511, Japan.ORCID http://orcid.org/0000-0002-0783-0758
Shigeyuki FurutaDepartment of Pediatric Surgery, St. Marianna University School of Medicine, 2-16-1 Sugao, Miyamae-Ku, Kawasaki, Kanagawa, 216-8511, Japan.
Miki SakamotoDepartment of Anesthesiology, St. Marianna University School of Medicine, 2-16-1 Sugao, Miyamae-Ku, Kawasaki, Kanagawa, 216-8511, Japan.
Juma ObayashiDepartment of Pediatric Surgery, St. Marianna University School of Medicine, 2-16-1 Sugao, Miyamae-Ku, Kawasaki, Kanagawa, 216-8511, Japan.
Dai KeinoKanagawa Children's Medical Center, 2-138-4 Mutsukawa, Minami-Ku, Yokohama, Kanagawa, 232-8555, Japan.
Kentaro NakamuraDepartment of Obstetrics and Gynecology, St. Marianna University School of Medicine, 2-16-1 Sugao, Miyamae-Ku, Kawasaki, Kanagawa, 216-8511, Japan.
Kunihide TanakaDepartment of Pediatric Surgery, St. Marianna University School of Medicine, 2-16-1 Sugao, Miyamae-Ku, Kawasaki, Kanagawa, 216-8511, Japan.
Takuya KawaguchiDepartment of Pediatric Surgery, St. Marianna University School of Medicine, 2-16-1 Sugao, Miyamae-Ku, Kawasaki, Kanagawa, 216-8511, Japan.
Mika MoriDepartment of Pediatrics, St. Marianna University School of Medicine, 2-16-1 Sugao, Miyamae-Ku, Kawasaki, Kanagawa, 216-8511, Japan.
Natsumi FuruyaDepartment of Obstetrics and Gynecology, St. Marianna University School of Medicine, 2-16-1 Sugao, Miyamae-Ku, Kawasaki, Kanagawa, 216-8511, Japan.
Mikiko NishiokaDepartment of Obstetrics and Gynecology, St. Marianna University School of Medicine, 2-16-1 Sugao, Miyamae-Ku, Kawasaki, Kanagawa, 216-8511, Japan.
Yuki Suzuki-TakahashiDepartment of Obstetrics and Gynecology, St. Marianna University School of Medicine, 2-16-1 Sugao, Miyamae-Ku, Kawasaki, Kanagawa, 216-8511, Japan.
Chiai NagaeDepartment of Pediatrics, St. Marianna University School of Medicine, 2-16-1 Sugao, Miyamae-Ku, Kawasaki, Kanagawa, 216-8511, Japan.
Yodo SugishitaDepartment of Obstetrics and Gynecology, St. Marianna University School of Medicine, 2-16-1 Sugao, Miyamae-Ku, Kawasaki, Kanagawa, 216-8511, Japan.
Yuki Horage-OkutsuDepartment of Obstetrics and Gynecology, St. Marianna University School of Medicine, 2-16-1 Sugao, Miyamae-Ku, Kawasaki, Kanagawa, 216-8511, Japan.
Tetsuya MoriDepartment of Pediatrics, St. Marianna University School of Medicine, 2-16-1 Sugao, Miyamae-Ku, Kawasaki, Kanagawa, 216-8511, Japan.
Naoki ShimizuDepartment of Pediatrics, St. Marianna University School of Medicine, 2-16-1 Sugao, Miyamae-Ku, Kawasaki, Kanagawa, 216-8511, Japan.
Hiroaki KitagawaDepartment of Pediatric Surgery, St. Marianna University School of Medicine, 2-16-1 Sugao, Miyamae-Ku, Kawasaki, Kanagawa, 216-8511, Japan.
Nao SuzukiDepartment of Obstetrics and Gynecology, St. Marianna University School of Medicine, 2-16-1 Sugao, Miyamae-Ku, Kawasaki, Kanagawa, 216-8511, Japan. nao@marianna-u.ac.jp.ORCID http://orcid.org/0000-0002-7440-8127

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundOvarian tissue cryopreservation (OTC) is recognized as the only option for fertility preservation in children. However, surgery for OTC in pediatric patients carries risks differing significantly from those in adults, and little is known about its safety. As a representative fertility preservation center in Japan, we investigated safety and feasibility of surgery for OTC in children.

methodsThe survey period was from November 2015 to November 2024. Data were collected retrospectively from the electronic medical records of 0- to 17-year-old girls who underwent OTC at our hospital. Age, primary disease, height, weight, comorbidities, operation time and blood loss, surgical complications, and changes in blood data of subjects were verified.

resultsMean age of the 110 patients was 8.9 ± 5.0 years. Of the patients, 89 (80.9%) had malignant diseases, with leukemia (n = 21. 19.1%) as the most common underlying disease. Twenty patients (18.1%) had recurrent disease and 84 (76.4%) were undergoing surgery during chemotherapy and/or radiotherapy. Mean body mass index was 17.0 kg/m

conclusionsThese results suggest that laparoscopic surgery for OTC in children can be performed safely with the cooperation of experts from multiple medical fields.

Indexed as

CryopreservationFertility PreservationLaparoscopyOvariectomyOvaryAdolescentChildChild, PreschoolFemaleHumansInfantInfant, NewbornJapanRetrospective StudiesChild cancerFertility preservationLaparoscopic surgeryOvarian tissue cryopreservation

Identifiers

PMID40263197

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.