Evidence map›Paper›PMID 40262901›Full record

ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2025

Differentiating Reinforcement Learning and Episodic Memory in Value-Based Decisions in Parkinson's Disease.

Leila Montaser-Kouhsari, Jonathan Nicholas, Raphael T Gerraty, Daphna Shohamy

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors.

Leila Montaser-KouhsariDepartment of Neurology, Brigham and Women Hospital, Harvard University, Boston, Massachusetts 02115.
Jonathan NicholasZuckerman Mind Brain Behavior Institute, Columbia University, New York, New York 10025.ORCID https://orcid.org/0000-0002-2314-0765
Raphael T GerratyZuckerman Mind Brain Behavior Institute, Columbia University, New York, New York 10025.
Daphna ShohamyZuckerman Mind Brain Behavior Institute, Columbia University, New York, New York 10025 ds2619@columbia.edu.

Funding

Differentiating reward seeking and loss avoidance with reference-dependent learning modelsR01MH121093 · NIMH · COLUMBIA UNIV NEW YORK MORNINGSIDE · PI DAW, NATHANIEL DOUGLASS, SHOHAMY, DAPHNA · 2019 to 2022
$2.1M
NIMH NIH HHS R01 MH121093
6 · The paper itself

Abstract

Patients with Parkinson's disease (PD) are impaired at incremental reward-based learning. It is typically assumed that this impairment reflects a loss of striatal dopamine. However, many open questions remain about the nature of reward-based learning deficits in PD. Recent studies have found that even simple reward-based learning tasks rely on a combination of cognitive and computational strategies, including one-shot episodic memory. These findings raise questions about how incremental learning and episodic memory contribute to decision-making in PD. We tested healthy participants (

Indexed as

Decision MakingMemory, EpisodicParkinson DiseaseReinforcement, PsychologyAgedFemaleHumansMaleMiddle AgedRewarddecision-makingdopamineEpisodic memoryParkinson's diseasereinforcement learningstriatum

Identifiers

PMID40262901
PMCPMC12096037

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.