Evidence map›Paper›PMID 40262827›Full record

ReviewJournal of nuclear medicine technology2025

Illuminating the Hidden: Standardizing Cardiac MIBG Imaging for Sympathetic Dysfunction.

Justin G Peacock, Haley Majot, Avani T Bansal, Patrick Neshiwat, Kelsy Dimeff, Kalpna Prasad

Abstract readReview
In one paragraph

Review in Journal of nuclear medicine technology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Myocardial Sympathetic Innervation Imaging.Journal of nuclear medicine technology · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Justin G PeacockDepartment of Radiology, Walter Reed National Military Medical Center, Bethesda, Maryland; justin.peacock@usuhs.edu kalpna.prasad.civ@health.mil.
Haley MajotDepartment of Radiology, Geisinger Medical Center, Danville, Pennsylvania.
Avani T BansalThe Potomac School, The Science and Engineering Research Center, McLean, Virginia; and.
Patrick NeshiwatDepartment of Cardiology, Hartford Hospital, Hartford, Connecticut.
Kelsy DimeffDepartment of Radiology, Walter Reed National Military Medical Center, Bethesda, Maryland.
Kalpna PrasadDepartment of Radiology, Walter Reed National Military Medical Center, Bethesda, Maryland; justin.peacock@usuhs.edu kalpna.prasad.civ@health.mil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The heart's innervation relies on a delicate balance between the sympathetic and parasympathetic nervous systems, each using distinct neurotransmitters to regulate heart rate, contractility, and vascular tone. The sympathetic division primarily uses norepinephrine, whereas the parasympathetic division operates through acetylcholine. A range of diseases, through intrinsic and extrinsic mechanisms, can disrupt these neural pathways, resulting in autonomic dysfunction. This review highlights intrinsic causes such as dysautonomias, amyloidosis, diabetes mellitus, Parkinsonian syndromes, and Lewy body dementia, as well as extrinsic factors such as heart failure, myocardial ischemia, infarction, and drug-induced cardiotoxicity. This article examines the effects of various conditions on cardiac sympathetic innervation and highlights how

Indexed as

3-IodobenzylguanidineHeartSympathetic Nervous SystemHumans3-Iodobenzylguanidinecardiac 123I-MIBGcardiac autonomic dysfunctiondysautonomiasympathetic nervous system imaging

Identifiers

PMID40262827
PMCPMC12176009

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.