Evidence map›Paper›PMID 40262792›Full record

ArticlePsychiatry investigation2025

Pre-Treatment Perceived Social Support Is Associated With Chemotherapy-Induced Peripheral Neuropathy in Patients With Breast Cancer: A Longitudinal Study.

Joon Sung Shin, Sanghyup Jung, Geun Hui Won, Sun Hyung Lee, Jaehyun Kim, Saim Jung, Chan-Woo Yeom, Kwang-Min Lee, Kyung-Lak Son, Jang-Il Kim and 3 more

Abstract read
In one paragraph

Article in Psychiatry investigation, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Joon Sung ShinDepartment of Neuropsychiatry, Seoul National University Hospital, Seoul, Republic of Korea.
Sanghyup JungDepartment of Psychiatry and Behavioral Sciences, Seoul National University College of Medicine, Seoul, Republic of Korea.
Geun Hui WonDepartment of Psychiatry, Chungnam National University Sejong Hospital, Sejong, Republic of Korea.
Sun Hyung LeeDepartment of Neuropsychiatry, Seoul National University Hospital, Seoul, Republic of Korea.
Jaehyun KimDepartment of Medicine, The Central Force for National Defence, Republic of Korea Army Personnel Command, Yongin, Republic of Korea.
Saim JungDepartment of Psychiatry, Korea University Ansan Hospital, Ansan, Republic of Korea.
Chan-Woo YeomDepartment of Psychiatry, Uijeongbu Eulji Medical Center, Eulji University School of Medicine, Uijeongbu, Republic of Korea.
Kwang-Min LeeMind Lab the Place Psychiatric Clinic, Seoul, Republic of Korea.
Kyung-Lak SonDepartment of Psychiatry, Dongguk University Ilsan Hospital, Goyang, Republic of Korea.
Jang-Il KimDepartment of Surgery, Seoul National University College of Medicine, Seoul, Republic of Korea.
Sook Young JeonDepartment of Surgery, Kangnam Sacred Heart Hospital, Seoul, Republic of Korea.
Han-Byoel LeeDepartment of Surgery, Seoul National University College of Medicine, Seoul, Republic of Korea.
Bong-Jin HahmDepartment of Neuropsychiatry, Seoul National University Hospital, Seoul, Republic of Korea.

Funding

Ministry of Science and ICTNational Research Foundation of Korea 2019R1A2C1003675
6 · The paper itself

Abstract

objectivePrevious studies have reported an association between cancer-related symptoms and perceived social support (PSS). The objective of this study was to analyze whether Chemotherapy-Induced Peripheral Neuropathy (CIPN), a prevalent side effect of chemotherapy, varies according to PSS level using a validated tool for CIPN at prospective follow-up.

methodsA total of 39 breast cancer patients were evaluated for PSS using the Multidimensional Scale of Perceived Social Support (MSPSS) prior to chemotherapy and were subsequently grouped into one of two categories for each subscale: low-to-moderate PSS and high PSS. CIPN was prospectively evaluated using the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire-Chemotherapy-Induced Peripheral Neuropathy 20 (CIPN20) at five time points. A linear mixed-effects model with square root transformation was employed to investigate whether the CIPN20 scales varied by PSS level and time point.

resultsStatistical analysis of the MSPSS total scale and subscales revealed a significant effect of the friends subscale group and time point on the CIPN20 sensory scale. The sensory scale score of CIPN20 was found to be lower in participants with high PSS from friends in comparison to those with low-to-moderate PSS at 1 month post-chemotherapy (p=0.010).

conclusionThis is the first study to prospectively follow the long-term effect of pre-treatment PSS from friends on CIPN. Further studies based on larger samples are required to analyze the effects of PSS on the pathophysiology of CIPN.

Indexed as

Adverse effectBreast cancerChemotherapyChemotherapy-induced peripheral neuropathyPerceived social support

Identifiers

PMID40262792
PMCPMC12022789

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