Evidence map›Paper›PMID 40262579›Full record

ArticleThe American journal of tropical medicine and hygiene2025

Disseminated Cutaneous Leishmaniasis Caused by Leishmania major in Immunocompetent Sudanese Child.

Abdelsalam Nail, Elwaleed M Elamin, Omaima Abdel Majeed Salih, Yousif M Kordofani, Musa M Kheir, Maowia M Mukhtar

Abstract readCase Reports
In one paragraph

Article in The American journal of tropical medicine and hygiene, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Abdelsalam NailDepartment of Internal Medicine, Faculty of Medicine, Omdurman Islamic University, Tropical Diseases Teaching Hospital, Omdurman, Sudan.
Elwaleed M ElaminFaculty of Medical Laboratories, Alzaim Alazhary University, Bioscience Research Institute, Khartoum, Sudan.
Omaima Abdel Majeed SalihDepartment of Paediatrics and Child Health, Faculty of Medicine and Health Sciences, Odurman Islamic University, Tropical Diseases Hospital, Omdurman, Sudan.
Yousif M KordofaniTropical Diseases Teaching Hospital, Omdurman, Sudan.
Musa M KheirTropical Diseases Teaching Hospital, Omdurman, Sudan.
Maowia M MukhtarBioscience Research Institute, Khartoum, Sudan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Leishmania major is the predominant cause of cutaneous leishmaniasis (CL) in Sudan. The disease frequently presents as localized skin lesions that usually heals spontaneously. A 10-year-old girl from Darfur, presented to Khartoum Dermatology Hospital with a 1-year history of widespread skin lesions. The lesions began as small papules on her upper and lower limbs and progressively involved all exposed areas, including her face, over 5 months. Diagnosis was confirmed by parasitology and culture from lesions aspirates. Leishmania major was identified by polymerase chain reaction. The patient was initially treated with intramuscular sodium stibogluconate (10 mg/kg) for 1 month, with no significant improvement. Subsequently, intravenous liposomal amphotericin B (Ambisome) was administered at a dose of 2.5 mg/kg daily in dextrose 5% for 14 days. Marked clinical improvement was observed, with lesions beginning to heal. Treatment was extended for an additional 40 days. The patient showed full recovery, with healed lesions leaving scars.

Indexed as

Leishmania majorLeishmaniasis, CutaneousAmphotericin BAntimony Sodium GluconateAntiprotozoal AgentsChildFemaleHumansImmunocompetenceSudanAmphotericin BAntimony Sodium GluconateAntiprotozoal Agentsliposomal amphotericin B

Identifiers

PMID40262579
PMCPMC12225553

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.