Evidence map›Paper›PMID 40262571›Full record

ArticleThe American journal of tropical medicine and hygiene2025

Serological Analysis Indicating the Exposure of Two Volunteers to Relapsing Fever Borrelia sp. in Nayarit, Mexico.

Sofía L Luna-Rojas, Edwin Vázquez-Guerrero, Jose A Hernández-Martínez, Jeanet Serafín-López, Fernando Martínez-Hernández, José Alejandro Martinez-Ibarra, Rigoberto Hernández-Castro, Job E López, J Antonio Ibarra

Abstract read
In one paragraph

Article in The American journal of tropical medicine and hygiene, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Sofía L Luna-RojasLaboratorio de Genética Microbiana, Departamento de Microbiología, Escuela Nacional de Ciencias Biológicas, Instituto Politécnico Nacional, Mexico City, Mexico.
Edwin Vázquez-GuerreroLaboratorio de Genética Microbiana, Departamento de Microbiología, Escuela Nacional de Ciencias Biológicas, Instituto Politécnico Nacional, Mexico City, Mexico.
Jose A Hernández-MartínezLaboratorio de Genética Microbiana, Departamento de Microbiología, Escuela Nacional de Ciencias Biológicas, Instituto Politécnico Nacional, Mexico City, Mexico.
Jeanet Serafín-LópezDepartamento de Inmunología, Escuela Nacional de Ciencias Biológicas, Instituto Politécnico Nacional, Mexico City, Mexico.
Fernando Martínez-HernándezDepartment of Ecology of Pathogens, General Hospital "Dr. Manuel Gea González", Mexico City, Mexico.
José Alejandro Martinez-IbarraLaboratorio de Entomología Médica, Departamento de Ciencias de la Naturaleza, Centro Universitario del Sur, Universidad de Guadalajara, Guadalajara, Mexico.
Rigoberto Hernández-CastroDepartment of Ecology of Pathogens, General Hospital "Dr. Manuel Gea González", Mexico City, Mexico.
Job E LópezDepartment of Pediatrics, National School of Tropical Medicine, Baylor College of Medicine, Houston, Texas.
J Antonio IbarraLaboratorio de Genética Microbiana, Departamento de Microbiología, Escuela Nacional de Ciencias Biológicas, Instituto Politécnico Nacional, Mexico City, Mexico.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Relapsing fever caused by Borrelia sp. is a neglected disease in Mexico and more studies are needed to update its presence in multiple regions of the country. Here, recombinant proteins glycerophosphodiester phosphodiesterase (GlpQ) and three Borrelia immunogenic protein A (BipA) variants were used for serosurveillance in 142 human serum samples. Results showed that two persons were positive to Borrelia extracts and GlpQ but negative to all three BipA, suggesting they were infected by relapsing fever spirochetes of a yet to be determined species. This shows that testing for GlpQ and Borrelia extracts are a useful tool for potential infections and grants their use in other regions and studies in Mexico.

Indexed as

Antibodies, BacterialBorreliaRelapsing FeverAdultAntigens, BacterialBacterial ProteinsFemaleHumansMaleMexicoPhosphoric Diester HydrolasesAntibodies, BacterialAntigens, BacterialBacterial ProteinsglpQ protein, BacteriaPhosphoric Diester Hydrolases

Identifiers

PMID40262571
PMCPMC12225586

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.