Evidence map›Paper›PMID 40262110›Full record

ReviewJournal of Alzheimer's disease : JAD2025

Precision neurocognition: An emerging diagnostic paradigm leveraging digital cognitive assessment technology.

David J Libon, Rodney Swenson, Dianne Teresa Langford, Stephanie Cosentino, Catherine C Price, Melissa Lamar, Sheina Emrani, Rhoda Au, Stacy Andersen, Michelle H Chen and 2 more

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Journal of Alzheimer's disease : JAD, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Validation of a Web-Based Digit Symbol Substitution Task for Detection of Mild Cognitive Impairment in Older Adults.Archives of clinical neuropsychology : the official journal of the National Academy of Neuropsychologists · 2026
    Article
  5. Article
  6. Article
  7. Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

David J LibonRowan University, School of Osteopathic Medicine, New Jersey Institute for Successful Aging, Stratford, NJ, USA.ORCID 0000-0001-6617-6066
Rodney SwensonUniversity of North Dakota School of Medicine and Health Sciences, Department of Psychiatry and Behavioral Neuroscience, Grand Forks, ND, USA.ORCID 0000-0003-4939-5405
Dianne Teresa LangfordRowan University, School of Osteopathic Medicine, Department of Neuroscience, Stratford, NJ, USA.
Stephanie CosentinoColumbia University Medical Center, Department of Neurology, Cognitive Neuroscience Division, Taub Institute and Sergievsky Center, New York, NY, USA.
Catherine C PriceUniversity of Florida, Department of Clinical and Health Psychology, Gainesville, FL, USA.
Melissa LamarRush Alzheimer's Disease Center and the Department of Psychiatry and Behavioral Sciences, Rush University Medical Center, Chicago, IL, USA.ORCID 0000-0001-6130-5543
Sheina EmraniDepartment of Neurology, University of Pennsylvania, Philadelphia, PA, USA.ORCID 0000-0002-1235-5285
Rhoda AuDepartment of Anatomy and Neurobiology, and Neurology, and the Framingham Heart Study, Boston University Chobanian & Avedisian School of Medicine, and Department of Epidemiology, Boston University School of Public Health, Boston, MA, USA.ORCID 0000-0001-7742-4491
Stacy AndersenDepartment of Medicine, Boston University Chobanian & Avedisian School of Medicine, Boston, MA, USA.ORCID 0000-0002-2442-6386
Michelle H ChenInstitute for Health, Health Care Policy and Aging Research Department of Neurology, Robert Wood Johnson Medical School Rutgers, The State University of New Jersey, New Brunswick, NJ, USA.ORCID 0000-0002-5689-0044
Lee AshendorfDepartment of Psychiatry, University of Massachusetts Chan Medical School and VA Central Western Massachusetts, Worcester, MA, USA.ORCID 0000-0003-0479-4023
Louisa ThompsonDepartment of Psychiatry and Human Behavior, Warren Alpert Medical School of Brown University, Providence, RI, USA.ORCID 0000-0002-7231-870X

Funding

Research Education CoreP30AG066462 · NIA · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI STEPHANIE Ann COSENTINO · 2020 to 2026
$30.1M
Accelerating digital cognitive screening for Alzheimer's disease in the Primary Care SettingK23AG080159 · NIA · BROWN UNIVERSITY · PI Louisa Thompson · 2023 to 2026
$721k
Validation of the DCTclock drawing task as a cognitive screening tool for prodromal Alzheimers disease in the Framingham Heart StudyR21AG072588 · NIA · BROWN UNIVERSITY · PI THOMPSON, LOUISA · 2021 to 2022
$392k
NIA NIH HHS K23 AG080159NIA NIH HHS P30 AG066462NIA NIH HHS R21 AG072588
6 · The paper itself

Abstract

Strategies that may modify Alzheimer's disease (AD) and other dementia disorders are being developed. To maximize the benefits of these strategies, it is critical that indicators suggesting neurocognitive decline are identified as early as possible. '

Indexed as

CognitionCognitive DysfunctionNeuropsychological TestsAlzheimer DiseaseDigital TechnologyHumansAlzheimer's diseaseBackward Digit Span TestBoston Process Approachdigital assessmentdigital neuropsychologyepisodic memoryexecutive controlmild cognitive impairmentPhiladelphia (repeatable) Verbal Learning Testprecision neurocognition

Identifiers

PMID40262110
PMCPMC12513561

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.