Evidence map›Paper›PMID 40261925›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2025

Phospholipid flippase ATP11A brokers uterine epithelial integrity and function.

Alexa Krala, Aleksandra O Tsolova, Bethany N Radford, Anshul S Jadli, Xiang Zhao, Danielle Blackwell, Ankita Narang, Wendy Dean, Myriam Hemberger

Abstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Phospholipid flippase ATP11A brokers uterine epithelial integrity and function.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Alexa KralaDepartment of Biochemistry and Molecular Biology, Cumming School of Medicine, University of Calgary, Calgary, AB T2N 4N1, Canada.ORCID 0000-0001-9257-528X
Aleksandra O TsolovaDepartment of Biochemistry and Molecular Biology, Cumming School of Medicine, University of Calgary, Calgary, AB T2N 4N1, Canada.ORCID 0000-0002-0273-5815
Bethany N RadfordDepartment of Biochemistry and Molecular Biology, Cumming School of Medicine, University of Calgary, Calgary, AB T2N 4N1, Canada.ORCID 0000-0001-8917-6800
Anshul S JadliDepartment of Biochemistry and Molecular Biology, Cumming School of Medicine, University of Calgary, Calgary, AB T2N 4N1, Canada.
Xiang ZhaoAlberta Children's Hospital Research Institute, University of Calgary, Calgary, AB T2N 4N1, Canada.ORCID 0009-0008-5326-3855
Danielle BlackwellDepartment of Biochemistry and Molecular Biology, Cumming School of Medicine, University of Calgary, Calgary, AB T2N 4N1, Canada.ORCID 0000-0002-0529-1199
Ankita NarangAlberta Children's Hospital Research Institute, University of Calgary, Calgary, AB T2N 4N1, Canada.ORCID 0000-0002-2948-7866
Wendy DeanAlberta Children's Hospital Research Institute, University of Calgary, Calgary, AB T2N 4N1, Canada.ORCID 0000-0001-9441-5044
Myriam HembergerDepartment of Biochemistry and Molecular Biology, Cumming School of Medicine, University of Calgary, Calgary, AB T2N 4N1, Canada.ORCID 0000-0003-3332-6958

Funding

Canadian Government | Canadian Institutes of Health Research (CIHR) CRC-2018-00240Canadian Government | Canadian Institutes of Health Research (CIHR) PJT-174982Canadian Government | Natural Sciences and Engineering Research Council of Canada (NSERC) RGPIN-2021-02417 to M.H.U of C | Alberta Children's Hospital Research Institute (ACHRI) HHDRPU of C | Alberta Children's Hospital Research Institute (ACHRI) N/A
6 · The paper itself

Abstract

Uterine adaptations driven by the steroid hormones estrogen and progesterone are pivotal for embryo implantation and, ultimately, for a successful pregnancy. Here, we show in mice that genetic ablation of the membrane lipid flippase

Indexed as

UterusAnimalsCell DifferentiationEmbryo ImplantationEpithelial CellsFemaleMiceMice, KnockoutPregnancyTrophoblastscell membranedevelopmentheartplacentauterus

Identifiers

PMID40261925
PMCPMC12054786

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.