Evidence map›Paper›PMID 40261885›Full record

ArticlePloS one2025

Population interest in and adequacy of the information on the safety of antineoplastic agents in the Spanish edition of Wikipedia.

Seira Climent-Ballester, Pedro García-Salom, Javier Sanz-Valero

Abstract read
In one paragraph

Article in PloS one, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Seira Climent-BallesterPharmacy Service, Dr. Balmis General University Hospital, Alicante, Spain.
Pedro García-SalomPharmacy Service, Dr. Balmis General University Hospital, Alicante, Spain.
Javier Sanz-ValeroCarlos III Health Institute, National School of Occupational Medicine, Madrid, Spain.ORCID 0000-0002-8735-0075

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo analyse the trend in use of the main antineoplastic agents (ANP) in Spain, to determine the association of this trend with the number of visits to the related pages in the Spanish edition of Wikipedia and to verify the existence of information aimed at reducing the associated risks of exposure to these drugs.

methodsThis study had an ecological, descriptive cross-sectional design. The ANP for which more than 100,000 units were used per year in the Spanish Health System were included in the analyses. The trend in the use of these ANP and the number of visits to the pages for these ANP in Wikipedia were analysed using a regression model, and the correlation of these variables was evaluated. Fulfilment of the criteria related to medical-pharmaceutical information (MPI) and safety measure information (SMI) was determined.

resultsAn increasing trend in the use of ANP was observed for the 9 ANP included in this study: paclitaxel, fluorouracil, azacitidine, oxaliplatin, rituximab, carboplatin, doxorubicin, etoposide, cyclophosphamide, and fluorouracil, which were the most commonly used ANP in the study period. Visits to the Wikipedia pages for the 9 ANP showed a decreasing trend, with an inverse relationship between use and visits to the related Wikipedia pages. Regarding MPI criteria, only the indication/use was included in all ANP pages, and no more than 30% of the remaining criteria were met, with the exception of rituximab, for which 50% of the remaining criteria were met. The SMI criteria were not fulfilled by the ANP pages; effects on fertility were included in 2 (22%) ANP pages and effects on pregnancy were included in 4 (44%) ANP pages. A molecular identifier appeared in 7 of the ANP pages.

conclusionsThe consumption of ANP increased, whereas the population interest in visiting related Wikipedia pages decreased. Neither MFI nor SMI were readily available in the ANP articles (pages), including information on the risk of exposure to these dangerous drugs or how to reduce this risk.

Indexed as

Antineoplastic AgentsInternetCross-Sectional StudiesHumansSpainAntineoplastic Agents

Identifiers

PMID40261885
PMCPMC12013910

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