ArticleACS applied materials & interfaces2025
Bioactive Polyurethane Shape Memory Polymer Foam Dressings with Enhanced Blood and Cell Interactions for Improved Wound Healing.
Article in ACS applied materials & interfaces, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
6 citing papers in PubMed.
- Body-responsive shape-memory polymers for biomedical applications.Bioactive materials · 2026Review
- Advanced Design Concepts for Shape-Memory Polymers in Biomedical Applications and Soft Robotics.Polymers · 2026Review
- Smart Biomaterials in Wound Healing: Advances, Challenges, and Future Directions in Intelligent Dressing Design.Bioengineering (Basel, Switzerland) · 2025Review
- In Vitro Characterization of Biodegradable Polyurethane Foams With Facile Gelatin Modification for Traumatic Wound Hemostasis and Regeneration.Journal of biomedical materials research. Part A · 2025Article
- Advanced wound healing with Stimuli-Responsive nanozymes: mechanisms, design and applications.Journal of nanobiotechnology · 2025Review
- Advances in Shape Memory Polymer Porous Materials: Fabrications, Microstructures, and Applications.Research (Washington, D.C.) · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
Polyurethane (PUr) shape memory polymer (SMP) foams have demonstrated excellent bleeding control in traumatic wounds. Unlike the current clinically available treatment options, PUr SMP foams can address noncompressible bleeds, are safe for prolonged use, and are highly tunable, offering broad functionalities like biodegradation and antimicrobial properties. Despite their hemostatic efficacy, PUrs are entirely synthetic, which limits their long-term healing capacity if left in a wound to degrade. This work employed methods for facile incorporation of bioactive collagen and gelatin into PUr foams postfabrication to enhance their clotting efficacy and drive cell interactions. The procoagulant nature of collagen and gelatin increased the clotting accomplished by the PUr SMP foams. Additionally, the bioactive PUr SMP foams promoted cell attachment, spreading, and proliferation on foam pores, which could facilitate tissue migration into the scaffold and promote wound repair. Overall, a bioactive PUr SMP foam dressing could significantly improve traumatic wound healing outcomes.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.