Evidence map›Paper›PMID 40261575›Full record

ArticleEuropean geriatric medicine2025

The impact of a multifaceted intervention on antibiotic use for common infections in nursing homes in Spain. A before and after study.

Ramon Monfà, Ana García-Sangenís, Rosa Morros, Carlota Manuela Zárate Sáez, Jesús Mateos-Nozal, María N Vaquero Pinto, Carmen Sáez Bejar, Elena López Pérez, Consuelo Rodríguez Jiménez, Rosa Magallón-Botaya and 3 more

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In one paragraph

Article in European geriatric medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Ramon MonfàFundació Institut Universitari per a la Recerca a l'Atenció Primària de Salut Jordi Gol, Barcelona, Spain.
Ana García-SangenísFundació Institut Universitari per a la Recerca a l'Atenció Primària de Salut Jordi Gol, Barcelona, Spain.
Rosa MorrosFundació Institut Universitari per a la Recerca a l'Atenció Primària de Salut Jordi Gol, Barcelona, Spain.
Carlota Manuela Zárate SáezDepartment of Geriatrics, Hospital Universitario Ramón y Cajal (IRYCIS), Madrid, Spain.ORCID http://orcid.org/0000-0001-6644-717X
Jesús Mateos-NozalDepartment of Geriatrics, Hospital Universitario Ramón y Cajal (IRYCIS), Madrid, Spain.
María N Vaquero PintoDepartment of Geriatrics, Hospital Universitario Ramón y Cajal (IRYCIS), Madrid, Spain.
Carmen Sáez BejarDepartment of Internal Medicine, Hospital Universitario La Princesa, Instituto de Investigación Sanitaria (IIS-Princesa), Madrid, Spain.
Elena López PérezInstitut Català de la Salut, Barcelona, Spain.
Consuelo Rodríguez JiménezDepartment of Pharmacology, Complejo Hospitalario Universitario de Canarias, Santa Cruz de Tenerife, Spain.
Rosa Magallón-BotayaGroup B21-23R, Health Research Institute of Aragon (IISA), Saragossa, Spain.
Priscila MatovelleDepartment of Geriatrics, Hospital San Juan de Dios, Saragossa, Spain.
Alicia Navarro SanmartínNursing Home, Aragon Institute of Social Services (IASS), Borja, Spain.
Carl LlorFundació Institut Universitari per a la Recerca a l'Atenció Primària de Salut Jordi Gol, Barcelona, Spain. carles.llor@gmail.com.

Funding

Mayo Clinic 71388143
6 · The paper itself

Abstract

purposeThe aim of this study was to assess the impact of a multifaceted intervention aimed at nursing home staff on antibiotic use and hygiene elements for nursing home residents with common infections.

methodsBefore-and-after study carried out in nursing homes in five areas of Spain. Nursing staff registered residents with common infections and documented hygiene practices over three months, before and after a 2-h educational intervention in autumn 2023. The intervention focused on the initial registration results, antibiotic guidelines, infection prevention, and management strategies for nursing homes. Indicators for potentially unnecessary antibiotic use and non-first-line antibiotics were developed, and results from both registration periods (Feb-Apr 2023 and Feb-Apr 2024) were compared to assess impact.

resultsOf 34 nursing homes, 23 completed the intervention and the two registrations (67.6%). Staff reported 1003 infections in the first registration and 789 in the second. The overall antibiotic prescription rate was 84.6%. Potentially inappropriate antibiotic use for urinary tract infections decreased from 70.3 to 59.9% (P < 0.005) and use for respiratory infections dropped from 78.1 to 62.7% (P < 0.001), with inappropriate use decreasing from 46.3 to 31% (P < 0.001). The mean duration of antibiotics for cystitis reduced from 7 to 5.4 days (P < 0.05). The intervention had no impact on hygiene practices.

conclusionPotentially unnecessary antibiotic use was lower after the intervention, whereas hygiene practices were unchanged. A more intensive, multifaceted educational approach is needed for a greater impact.

Indexed as

Anti-Bacterial AgentsHomes for the AgedInappropriate PrescribingNursing HomesNursing StaffAgedAged, 80 and overFemaleGuideline AdherenceHumansMaleRespiratory Tract InfectionsSpainUrinary Tract InfectionsAnti-Bacterial AgentsAnti-bacterial agentsAntimicrobial stewardshipFrail elderlyHygieneMedical auditNursing homesOverdiagnosis

Identifiers

PMID40261575
PMCPMC12378843

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.