Evidence map›Paper›PMID 40261572›Full record

ArticleRadiological physics and technology2025

A CT-free deep-learning-based attenuation and scatter correction for copper-64 PET in different time-point scans.

Zahra Adeli, Seyed Abolfazl Hosseini, Yazdan Salimi, Nasim Vahidfar, Peyman Sheikhzadeh

Abstract read
PubMed Publisher
In one paragraph

Article in Radiological physics and technology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Zahra AdeliGroup of Medical Radiation Engineering, Department of Energy Engineering, Sharif University of Technology, Tehran, Iran.
Seyed Abolfazl HosseiniGroup of Medical Radiation Engineering, Department of Energy Engineering, Sharif University of Technology, Tehran, Iran. sahosseini@sharif.edu.
Yazdan SalimiDivision of Nuclear Medicine and Molecular Imaging, Geneva University Hospital, Geneva, Switzerland.
Nasim VahidfarDepartment of Nuclear Medicine, Faculty of Medicine, IKHC, Tehran University of Medical Sciences, Tehran, Iran.
Peyman SheikhzadehDepartment of Nuclear Medicine, Faculty of Medicine, IKHC, Tehran University of Medical Sciences, Tehran, Iran. psh82@yahoo.com.ORCID http://orcid.org/0000-0003-3053-2641

Funding

Tehran University of Medical Sciences and Health Services 90014
6 · The paper itself

Abstract

This study aimed to develop and evaluate a deep-learning model for attenuation and scatter correction in whole-body 64Cu-based PET imaging. A swinUNETR model was implemented using the MONAI framework. Whole-body PET-nonAC and PET-CTAC image pairs were used for training, where PET-nonAC served as the input and PET-CTAC as the output. Due to the limited number of Cu-based PET/CT images, a model pre-trained on 51 Ga-PSMA PET images was fine-tuned on 15 Cu-based PET images via transfer learning. The model was trained without freezing layers, adapting learned features to the Cu-based dataset. For testing, six additional Cu-based PET images were used, representing 1-h, 12-h, and 48-h time points, with two images per group. The model performed best at the 12-h time point, with an MSE of 0.002 ± 0.0004 SUV

Indexed as

Copper RadioisotopesDeep LearningImage Processing, Computer-AssistedPositron-Emission TomographyPositron Emission Tomography Computed TomographyScattering, RadiationHumansTime FactorsCopper-64Copper RadioisotopesAttenuation correctionDeep learningPositron emission tomography (PET)Scatter correctionSwinUNETRTransfer learning

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.