Evidence map›Paper›PMID 40261454›Full record

Trial reportOral and maxillofacial surgery2025

Evaluation of the effectiveness of dextrose injection in improving chewing function in patients with the temporomandibular joint closed lock: a pilot study.

Yazan Sayed Taleb, Mazen Zenati, Yasser Alsayed Tolibah

Abstract readRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in Oral and maxillofacial surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Yazan Sayed TalebDepartment of Oral and Maxillofacial Surgery, Damascus University, Damascus, Syria.
Mazen ZenatiDepartment of Oral and Maxillofacial Surgery, Damascus University, Damascus, Syria.
Yasser Alsayed TolibahDepartment of Pediatric Dentistry, Damascus University, Damascus, Syria. Yasseralsayedtolibah@gmail.com.ORCID http://orcid.org/0000-0001-5498-9991

Funding

Damascus University 501100020595
6 · The paper itself

Abstract

objectiveTo evaluate the intra-articular injection of 5% Dextrose efficacy in treating difficulty chewing patients with Temporomandibular Joint (TMJ) Closed Lock (CL). MATERIALS AND

methodsThis pilot study included twenty female patients suffering from symptoms of Disc Displacement without Reduction (DDwoR) with limited mouth opening (Closed Lock) mentioned in the Diagnostic Criteria for Temporomandibular Disorders (DC/TMD). Participants were randomly assigned into two groups; the study group patients were injected with D5W, while the control group patients were injected with 0.9% normal saline. The chewing Pain Index (CPI) was measured based on the criteria recommended by the International Association of Oral and Maxillofacial Surgeons (IAOMS) that assessed mandibular function by relating pain with the type of food eaten and using it as an index of improvement in function. The CPI was measured before and thrice after injection (2 weeks, 2 months, and 6 months). The significance level was set at α = 0.05.

resultsA decrease in the CPI grades was observed in both groups, with a significant difference in favor of the study group at all follow-up times(< 0.001).

conclusionD5W improved the chewing function in female closed-lock patients.

Indexed as

GlucoseMasticationTemporomandibular Joint DisordersAdultFemaleHumansInjections, Intra-ArticularMiddle AgedPain MeasurementPilot ProjectsTreatment OutcomeGlucose5% dextroseChewingClosed lockIntra-articular injection

Identifiers

PMID40261454

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.