Evidence map›Paper›PMID 40261447›Full record

ArticleArchives of virology2025

Circulation of non-polio enteroviruses in the Ural Federal District and Western Siberia in 2023: the return of an old foe?

Tarek M Itani, Vladislav I Chalapa, Vasilii N Slautin, Bolat S Imangaliev, Maria S Kungurtseva, Anastasia K Patrusheva, Aleksandr G Sergeev, Aleksandr V Semenov

Abstract read
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In one paragraph

Article in Archives of virology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Tarek M ItaniLaboratory of Enteric virus infections, Federal Budgetary Institution of Science «Federal Scientific Research Institute of Viral Infections «Virome»», Federal Service for Surveillance on Consumer Rights Protection and Human Wellbeing, Ekaterinburg, Russia. itani_tm@niivirom.ru.
Vladislav I ChalapaLaboratory of Enteric virus infections, Federal Budgetary Institution of Science «Federal Scientific Research Institute of Viral Infections «Virome»», Federal Service for Surveillance on Consumer Rights Protection and Human Wellbeing, Ekaterinburg, Russia.
Vasilii N SlautinLaboratory of Enteric virus infections, Federal Budgetary Institution of Science «Federal Scientific Research Institute of Viral Infections «Virome»», Federal Service for Surveillance on Consumer Rights Protection and Human Wellbeing, Ekaterinburg, Russia.
Bolat S ImangalievLaboratory of Enteric virus infections, Federal Budgetary Institution of Science «Federal Scientific Research Institute of Viral Infections «Virome»», Federal Service for Surveillance on Consumer Rights Protection and Human Wellbeing, Ekaterinburg, Russia.
Maria S KungurtsevaLaboratory of Enteric virus infections, Federal Budgetary Institution of Science «Federal Scientific Research Institute of Viral Infections «Virome»», Federal Service for Surveillance on Consumer Rights Protection and Human Wellbeing, Ekaterinburg, Russia.
Anastasia K PatrushevaLaboratory of Enteric virus infections, Federal Budgetary Institution of Science «Federal Scientific Research Institute of Viral Infections «Virome»», Federal Service for Surveillance on Consumer Rights Protection and Human Wellbeing, Ekaterinburg, Russia.
Aleksandr G SergeevLaboratory of Enteric virus infections, Federal Budgetary Institution of Science «Federal Scientific Research Institute of Viral Infections «Virome»», Federal Service for Surveillance on Consumer Rights Protection and Human Wellbeing, Ekaterinburg, Russia.
Aleksandr V SemenovLaboratory of Enteric virus infections, Federal Budgetary Institution of Science «Federal Scientific Research Institute of Viral Infections «Virome»», Federal Service for Surveillance on Consumer Rights Protection and Human Wellbeing, Ekaterinburg, Russia.

Funding

Russian Federal Service for Surveillance on Consumer Rights Protection and Human Wellbeing № 121041500041-1
6 · The paper itself

Abstract

Human non-polio enteroviruses (NPEVs) cause a wide range of illnesses such as hand, foot, and mouth disease (HFMD), herpangina, and aseptic meningitis. In this study, we investigated the incidence of NPEV infections in the Ural Federal District and Western Siberia, Russia, from 2019 to 2023 in patients with various NPEV-associated diseases, identified the main circulating genotypes in 2023, and analyzed their epidemiological characteristics. A total of 384 samples that tested positive by polymerase chain reaction (PCR) for NPEVs were genotyped by semi-nested PCR specific for the VP1 gene. A total of 20 genotypes were identified among the patients in this study, with enterovirus A accounting for 57.2% of all typed samples, enterovirus B accounting for 41%, and enterovirus C accounting for 1.8%. Coxsackievirus A6 (CVA6) was the most common genotype in HFMD cases. Echovirus 30 (E30) was predominant in aseptic meningitis patients, and coxsackievirus A2 was primarily associated with herpangina. Phylogenetic analysis showed that most of the CVA6 strains identified in this study displayed a close genetic relationship to strains that circulated in China, while E30 genotypes circulating in the studied region belonged to subgenotype V. Laboratory-based monitoring and epidemiological surveillance for genetic changes and evolutionary studies are necessary for improving prevention and clinical care.

Indexed as

EnterovirusEnterovirus InfectionsAdolescentAdultChildChild, PreschoolFemaleGenotypeHand, Foot and Mouth DiseaseHerpanginaHumansIncidenceInfantMaleMeningitis, AsepticMiddle Aged

Identifiers

PMID40261447

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.