Evidence map›Paper›PMID 40261425›Full record

ArticleClinical research in cardiology : official journal of the German Cardiac Society2025

Clinical use and predictors of outcome in venoarterial extracorporeal membrane (VA ECMO): insights from VERGE (VA ECMO Registry of Germany).

Tobias Wengenmayer, Dawid L Staudacher, Alois Philipp, Eike Tigges, Angela Dettling, Hendrik Busse, Marc Kriege, Jan-Sören Padberg, Ingo Voigt, Clemens Scherer and 6 more

Abstract readMulticenter Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Clinical research in cardiology : official journal of the German Cardiac Society, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Tobias Wengenmayer *Interdisciplinary Medical Intensive Care (IMIT), Faculty of Medicine and Medical Center, University of Freiburg, Freiburg, Germany.
Dawid L Staudacher *Interdisciplinary Medical Intensive Care (IMIT), Faculty of Medicine and Medical Center, University of Freiburg, Freiburg, Germany. dawid.staudacher@uniklinik-freiburg.de.ORCID http://orcid.org/0000-0002-9423-9682
Alois PhilippDepartment of Cardiothoracic Surgery, University Medical Center Regensburg, Regensburg, Germany.
Eike TiggesAsklepios Clinic St. Georg, Cardiology and Critical Care, Hamburg, Germany.
Angela DettlingUniversity Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Hendrik BusseHeart and Vascular Center Bad Bevensen, Bad Bevensen, Germany.
Marc KriegeDepartment of Anesthesiology, University Medical Center, Johannes Gutenberg-University, Mainz, Germany.
Jan-Sören PadbergDepartment for Cardiology I: Coronary and Periphereal Vascular Disease, Heart Failure, University Hospital Münster, Münster, Germany.
Ingo VoigtDepartment of Acute and Emergency Medicine, Elisabeth-Hospital Essen, Essen, Germany.
Clemens SchererDepartment of Medicine I, LMU University Hospital, LMU Munich, Munich, Germany.
Tobias GrafUniversity Heart Center Lübeck, Lübeck, Germany.
Dominik ScharpfSLK-Kliniken Heilbronn GmbH, Klinikum Am Gesundbrunnen, Medical Department I, Heilbronn, Germany.
Peter NoackDepartment of Cardiology, Intensive Care Medicine, Klinikum Nürnberg, Paracelsus Medical University, Nuremberg, Germany.
Simone BritschCentre for Acute Cardiovascular Medicine Mannheim (DZKAM), Department of Cardiology, Angiology, Haemostaseology and Medical Intensive Care, University Medical Centre Mannheim, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.
Guido MichelsDepartment of Emergency Medicine, Hospital of the Barmherzige Brüder, Trier, Germany.
VERGE Study Group

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The VA ECMO Registry of Germany (VERGE, http://va-ecmo-register.de/ ) is a prospective, multicenter, investigator-driven registry of Venoarterial Extracorporeal Membrane Oxygenation (VA ECMO) all-comers, free from industrial support. VERGE is Germany's first multicenter registry to systematically gather and analyze data from various centers on the clinical use of VA ECMO. This first report compromises data from 581 VA ECMO patients from 2022. Median age was 60 years, hospital survival was 42% and 25% were female. The leading indication for VA ECMO was extracorporeal cardiopulmonary resuscitation (ECPR) followed by VA ECMO in shock (48.9 and 34.9%, respectively). Hospital survival of ECPR was significantly worse compared to shock (28 and 55%, respectively, p < 0.001). Age, pH, and lactate before cannulation all significantly correlated independently with hospital survival (p < 0.001). In VERGE, no patients with pH below 6.7 or lactate above 25 mmol/l survived.

Indexed as

Extracorporeal Membrane OxygenationRegistriesAdultAgedCardiopulmonary ResuscitationFemaleGermanyHospital MortalityHumansMaleMiddle AgedProspective StudiesRisk FactorsSurvival RateTreatment OutcomeExtracorporeal cardiopulmonary resuscitation (ECPR)Extracorporeal membrane oxygenation (ECMO)OutcomeShockSurvival

Identifiers

PMID40261425
PMCPMC12460512

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.