Evidence map›Paper›PMID 40261413›Full record

ArticleLangenbeck's archives of surgery2025

Transanal endoscopic microsurgery in the treatment of rectal neuroendocrine tumors: a retrospective 10-year single-center experience.

Marek Szczepkowski, Piotr Witkowski, Alicja Przywózka-Suwała, Karolina Skonieczna-Żydecka, Teresa Starzyńska, Krzysztof Dąbkowski

Abstract read
In one paragraph

Article in Langenbeck's archives of surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Rectal neuroendocrine tumors: Update.World journal of gastrointestinal oncology · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Marek SzczepkowskiClinical Department of Colorectal, General, and Oncological Surgery, Centre of Postgraduate Medical Education, Warsaw, Poland.
Piotr WitkowskiClinical Department of Colorectal, General, and Oncological Surgery, Centre of Postgraduate Medical Education, Warsaw, Poland.
Alicja Przywózka-SuwałaClinical Department of Colorectal, General, and Oncological Surgery, Centre of Postgraduate Medical Education, Warsaw, Poland.
Karolina Skonieczna-ŻydeckaDepartment of Biochemical Science, Pomeranian Medical University in Szczecin, Szczecin, Poland.
Teresa StarzyńskaDepartment of Gastroenterology, Pomeranian Medical University in Szczecin, Szczecin, Poland.
Krzysztof DąbkowskiDepartment of Gastroenterology, Pomeranian Medical University in Szczecin, Szczecin, Poland. dabkowskikrzysztof@wp.pl.ORCID https://orcid.org/0000-0002-5386-9004

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTransanal endoscopic surgery is a recommended full-thickness resection technique for the treatment of rectal neuroendocrine tumors. We aimed to compare the efficacy, safety and follow-up of patients with rectal neuroendocrine tumors treated with transanal endoscopic microsurgery in the primary setting and as salvage therapy after non-radical endoscopic polypectomy.

methodsA retrospective analysis of a 10-year database of patients treated with transanal endoscopic microsurgery was performed. The procedure-related measures, including duration of the procedure, adverse events, and patient-related measures, including age, gender, tumor size, grading, and length of follow-up, were obtained. We compared the primary TEM group with the salvage group.

resultsIn total, 30 patients with rectal neuroendocrine tumors were included in the study; 13 of them received primary treatment and 17 salvage therapy of the scar. Patients receiving primary treatment were significantly older (60.5 vs. 51.7 years). There were no significant differences in patient gender, tumor size and grading, length of follow-up, hospital stay or procedure time. The R0 resection rate was 92.3% in the primary treatment group. Adverse events were mild or managed with endoscopic treatment. Follow-up was slightly but not significantly longer in the primary treatment group and showed no recurrences in both groups of patients.

conclusionsTransanal endoscopic microsurgery is safe and effective for both primary and salvage treatment of rectal neuroendocrine tumors.

Indexed as

Neuroendocrine TumorsRectal NeoplasmsTransanal Endoscopic MicrosurgeryAdultAgedFemaleFollow-Up StudiesHumansMaleMicrosurgeryMiddle AgedRetrospective StudiesSalvage TherapyTreatment OutcomeRectal neuroendocrine tumorsSalvage therapyTEMTreatment

Identifiers

PMID40261413
PMCPMC12014771

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.