Evidence map›Paper›PMID 40261392›Full record

ArticleEuropean spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society2026

Redefining physiological whole-body alignment according to pelvic incidence: normative values and prediction models.

Marc Khalifé, Wafa Skalli, Claudio Vergari, Pierre Guigui, Valérie Attali, Rémi Valentin, Olivier Gille, Virginie Lafage, Han Jo Kim, Ayman Assi and 1 more

Abstract readMulticenter Study
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In one paragraph

Article in European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

11 authors.

Marc KhaliféHôpital Européen Georges-Pompidou, Paris, France. marc.khalife@aphp.fr.
Wafa SkalliInstitut de Biomécanique Humaine Georges Charpak, Paris, France.
Claudio VergariInstitut de Biomécanique Humaine Georges Charpak, Paris, France.
Pierre GuiguiHôpital Européen Georges-Pompidou, Paris, France.
Valérie AttaliNeurophysiologie Respiratoire Expérimentale et Clinique, Paris, France.
Rémi ValentinInstitut de Biomécanique Humaine Georges Charpak, Paris, France.
Olivier GilleHôpital Pellegrin, Bordeaux, France.
Virginie LafageLenox Hill Hospital, New York, USA.
Han Jo KimHospital for Special Surgery, New York, USA.
Ayman AssiSaint Joseph University, Beirut, Lebanon.
Emmanuelle FerreroHôpital Européen Georges-Pompidou, Paris, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background contextSpinopelvic alignment assessment needs to account for pelvic incidence (PI). PURPOSE: This study aimed at providing normative values for commonly used parameters in whole-body alignment analysis based on PI.

designMulticentric prospective study. PATIENT SAMPLE: This study included healthy volunteers with full-body biplanar radiograph in free-standing position. OUTCOME MEASURES: All radiographic data were collected from 3D reconstructions: Sagittal vertical axis (SVA), T1 pelvic angle (TPA), spino-sacral angle (SSA), sagittal odontoid-hip axis angle (ODHA), pelvic parameters, sacro-femoral angle (SFA), knee flexion angle (KFA), ankle flexion angle (AA), Pelvic shift (PSh), lumbar lordosis (LL), thoracic kyphosis (TK) and cervical lordosis (CL).

methodsPopulation was divided into five groups according to PI. Normative values were described for each group. Linear regressions including age and PI provided prediction formulas for PT, TPA, SSA and SFA.

results642 subjects were included. Mean age was 37.7 ± 16.3 years (range: 18-90). Mean PI in the cohort was 49.3 ± 9.5°. LL, PT, SFA, SSA and TPA correlated with PI and age. ODHA, TK, CL and the other lower limb parameters were not associated with PI. All normative values across PI groups are provided for segmental, regional and global alignment parameters. Prediction formulas were: PT=-12.7 + 0.38*PI + 0.14*Age, TPA=-16.9 + 0.34*PI + 0.15*Age, SSA = 109.8 + 0.58*PI-0.19*Age, and SFA = 173 + 0.39*PI + 0.11*Age.

conclusionsSSA, PT, TPA and SFA must be assessed according to patient's PI. This study provides normative values for each PI group, and predictive formulas taking age and PI into account. PI cannot be used to define thoracic and cervical curvatures. LEVEL OF EVIDENCE: II.

Indexed as

Pelvic BonesPelvisAdolescentAdultAgedAged, 80 and overFemaleHumansMaleMiddle AgedProspective StudiesRadiographyReference ValuesYoung AdultLumbar lordosisNormative valuesPelvic incidenceSagittal alignmentSpinal shape

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.