Evidence map›Paper›PMID 40261285›Full record

ArticleClinical and translational science2025

Recommended Clinical Context and Patient Context Data Elements for Liquid Biopsy Data Submitted to Data Repositories and Data Commons.

Robert L Grossman, Jake Vinson, Elizabeth Bain, Karl Bisselou, Sanchi Chandan, Carolyn Compton, John Hu, Donald J Johann, Frederick Jones, Gregory Jones and 12 more

Abstract read
In one paragraph

Article in Clinical and translational science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors.

Robert L GrossmanOpen Commons Consortium, Chicago, Illinois, USA.ORCID 0000-0003-3741-5739
Jake VinsonProstate Cancer Clinical Trials Consortium, New York, New York, USA.ORCID 0009-0000-0405-7854
Elizabeth BainAmerican Cancer Society, Atlanta, Georgia, USA.ORCID 0009-0003-2543-9394
Karl BisselouStreck, La Vista, Nebraska, USA.ORCID 0000-0002-4889-9233
Sanchi ChandanThermo Fisher Scientific, Carlsbad, California, USA.
Carolyn ComptonUniversity of Arizona, Tucson, Arizona, USA.ORCID 0000-0002-6904-2765
John HuEXACT Sciences, Madison, Wisconsin, USA.
Donald J JohannUniversity of Arkansas for Medical Sciences, Little Rock, Arkansas, USA.ORCID 0009-0002-3173-6910
Frederick JonesFormerly at Sysmex Inostics, Baltimore, Maryland, USA.ORCID 0000-0002-6534-8206
Gregory JonesFormerly at NeoGenomics Laboratories, Fort Myers, Florida, USA.
Suzanne LeBlangFocused Ultrasound Foundation, Charlottesville, Virginia, USA.
Jerry S H LeeUniversity of Southern California, Los Angeles, California, USA.ORCID 0000-0003-1515-0952
Tara LichtenbergUniversity of Chicago, Chicago, Illinois, USA.ORCID 0000-0003-4081-8854
Christina M LockwoodUniversity of Washington, Washington, Washington, USA.ORCID 0000-0001-9036-7604
John LylePersonalis, Fremont, California, USA.
Jean-Francois MartiniPfizer, San Diego, California, USA.ORCID 0000-0001-8570-1401
Jason D MerkerUniversity of North Carolina, Chapel Hill, North Carolina, USA.ORCID 0000-0002-0865-3394
Lauren SaundersCeres Nanosciences, Manassas, Virginia, USA.ORCID 0009-0003-3498-6496
Howard ScherMemorial Sloan Kettering Cancer Center, New York, New York, USA.
Stella SomiariWindber Research Institute, Windber, Pennsylvania, USA.ORCID 0000-0002-7170-9098
Jenny YouEXACT Sciences, Madison, Wisconsin, USA.
Lauren C LeimanBLOODPAC, Chicago, Illinois, USA.ORCID 0009-0002-4374-7246

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In 2020, BLOODPAC recommended 11 pre-analytical minimal technical data elements for collection and submission of liquid biopsy data to public databases. This article expands on that work by recommending 22 clinical context and 10 patient context data elements. These elements, essential for liquid biopsy data submitted to repositories like the BLOODPAC Data Commons, cover tumor characteristics, disease progression, and patient demographics, supporting biomarker validation, research, and clinical trials.

Indexed as

Biomarkers, TumorDatabases, FactualNeoplasmsDisease ProgressionHumansLiquid BiopsyBiomarkers, Tumorclinical context data elementsdata commonsliquid biopsypatient context data elements

Identifiers

PMID40261285
PMCPMC12013509

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.