Evidence map›Paper›PMID 40261158›Full record

SynthesisInternational wound journal2024

RETRACTED: Effects of exercise in treating patients with venous leg ulcers: An umbrella review.

Min Shen, Mengzhen Xing, Hehe Jiang, Linlin Zhang, Chen Chen, Yuning Ma, Yuxia Ma

RetractedAbstract readSystematic ReviewRetracted Publication
In one paragraph

Synthesis in International wound journal, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Min ShenShandong University of Traditional Chinese Medicine, Jinan, Shandong Province, China.
Mengzhen XingShandong University of Traditional Chinese Medicine, Jinan, Shandong Province, China.
Hehe JiangShandong University of Traditional Chinese Medicine, Jinan, Shandong Province, China.
Linlin ZhangShandong University of Traditional Chinese Medicine, Jinan, Shandong Province, China.
Chen ChenShandong University of Traditional Chinese Medicine, Jinan, Shandong Province, China.
Yuning MaShandong University of Traditional Chinese Medicine, Jinan, Shandong Province, China.
Yuxia MaShandong University of Traditional Chinese Medicine, Jinan, Shandong Province, China.

Funding

Jinan "GaoXiao 20 Tiao" Funding Project Contract 2020GXRC005Joint Fund of Natural Science Foundation of Shandong Province ZR2021LZY044Lu Wei Talent Word [2020]NATCM's Project of High-level Construction of Key TCM Disciplines zyyzdxk-2023116National Research and Training Program for Outstanding Clinical Talents of Traditional Chinese MedicineQilu Health Leading Talent ProjectShandong Natural Science Foundation ZR2021MH373
6 · The paper itself

Abstract

Venous leg ulcers (VLUs) represent a substantial challenge within the healthcare landscape, thereby necessitating efficacious therapeutic strategies. Exercise has been investigated as a prospective intervention to bolster the management of VLUs. The objective of this comprehensive review is to systematically scrutinize and appraise the extant body of evidence pertaining to the impact of exercise on the treatment of patients diagnosed with VLUs. A comprehensive literature search was executed across multiple databases, encompassing PubMed, the Cochrane Library, Web of Science, Embase, and Google Scholar. The methodological rigour was evaluated utilizing the Assessment of Multiple Systematic Reviews 2 (AMSTAR-2) instrument, while the quality of the evidence was appraised via the Grading of Recommendations Assessment, Development and Evaluation (GRADE) classification system. The relative efficacy of exercise interventions on outcomes related to VLUs, including rates of wound healing, total range of motion in the ankle joint, and adherence rates, was synthesized. Data were consolidated employing fixed-effects models, and the impact of exercise on these outcomes was visually represented through the use of forest plots. The methodological foundation of this investigation comprised four systematic reviews and meta-analyses, each characterized by an intermediate level of methodological rigour and evidence quality. Subsequent analyses revealed that exercise interventions exert a multifaceted and favourable impact on the therapeutic landscape of VLUs. These interventions distinctly contribute to the enhancement of wound healing rates (risk difference 0.17, 95% confidence interval [CI]: 0.06-0.28) and the extension of ankle range of motion (mean difference [MD] 6.10, 95% CI: 4.61-7.59). Furthermore, Pooled adherence rate was 0.70 (95% CI: 0.20-2.45) with no significant heterogeneity. In conclusion, although existing evidence supports the positive impact of exercise training on VLUs, higher-quality research is still needed to deepen our understanding of its effects and provide more specific guidance for clinical practice.

Indexed as

Exercise TherapyVaricose UlcerWound HealingHumansTreatment Outcomeevidenceexercisemeta‐analysessystematic reviewsvenous leg ulcers

Identifiers

PMID40261158
PMCPMC10830917

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.