Evidence map›Paper›PMID 40260403›Full record

ReviewFrontiers in molecular biosciences2025

FOXOs and their roles in acute and chronic neurological disorders.

Yasin Asadi, Rozenn K Moundounga, Anand Chakroborty, Augustina Pokokiri, Hongmin Wang

Abstract readReview
In one paragraph

Review in Frontiers in molecular biosciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Yasin AsadiDepartment of Pharmacology and Neuroscience, Texas Tech University Health Sciences Center, Lubbock, TX, United States.
Rozenn K MoundoungaDepartment of Pharmacology and Neuroscience, Texas Tech University Health Sciences Center, Lubbock, TX, United States.
Anand ChakrobortyDepartment of Pharmacology and Neuroscience, Texas Tech University Health Sciences Center, Lubbock, TX, United States.
Augustina PokokiriDepartment of Pharmacology and Neuroscience, Texas Tech University Health Sciences Center, Lubbock, TX, United States.
Hongmin WangDepartment of Pharmacology and Neuroscience, Texas Tech University Health Sciences Center, Lubbock, TX, United States.

Funding

FOXOs in ischemic strokeR01NS124846 · NINDS · UNIVERSITY OF SOUTH DAKOTA · PI Hongmin Wang · 2022 to 2026
$1.9M
Priming the proteasome to protect against aging and Alzheimer's diseaseRF1AG072510 · NIA · UNIVERSITY OF SOUTH DAKOTA · PI WANG, HONGMIN, WANG, XUEJUN · 2022 to 2022
$1.6M
Priming the proteasome to protect against aging and Alzheimer's diseaseR01AG072510 · NIA · UNIVERSITY OF SOUTH DAKOTA · PI XUEJUN WANG, Hongmin Wang · 2025 to 2026
$1.0M
NIA NIH HHS R01 AG072510NIA NIH HHS RF1 AG072510NINDS NIH HHS R01 NS124846
6 · The paper itself

Abstract

The forkhead family of transcription factors of class O (FOXOs) consisting of four functionally related proteins, FOXO1, FOXO3, FOXO4, and FOXO6, are mammalian homologs of daf-16 in

Indexed as

Alzheimer’s diseasebrainforkhead transcription factorsFOXOHuntington’s diseaseinjuryneuronstroke

Identifiers

PMID40260403
PMCPMC12010098

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.