ReviewFrontiers in pharmacology2025
Multi-target mechanisms and potential applications of quercetin in the treatment of acne vulgaris.
Review in Frontiers in pharmacology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
4 citing papers in PubMed.
- Large-scale comparative virtual screening identifies novel molecular targets underlying the multi-target activity of quercetin in psoriasis.Inflammopharmacology · 2026Article
- Comprehensive analysis of phenotypes and transcriptome characteristics reveal important contribution of chronic stress and inflammation in the pathogenesis of acne.Bioscience reports · 2026Article
- Mechanism of Artemisia annua active component quercetin in treating psoriasis by regulating ferroptosis.Scientific reports · 2026Article
- Advances in Bioprinting to Model Immune-Mediated Skin Diseases.Advanced healthcare materials · 2026Review
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Acne vulgaris, a prevalent inflammatory dermatosis, afflicts approximately 90% of adolescents globally. Despite the efficacy of conventional therapies, including antibiotics and retinoids, their use is frequently limited by adverse effects and the emergence of drug resistance. Quercetin, a naturally occurring flavonoid, has garnered significant attention owing to its diverse biological activities, encompassing anti-inflammatory, antioxidant, antimicrobial, and immunomodulatory properties. This review comprehensively explores the multi-target mechanisms of quercetin in the treatment of acne, focusing on its ability to modulate inflammatory cytokine production, oxidative stress pathways, sebaceous gland activity, and microbial populations. Additionally, quercetin promotes skin barrier repair and reduces post-inflammatory hyperpigmentation and scarring through its antioxidant and anti-fibrotic effects. Despite promising
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.